成人胸膜肺母细胞瘤临床及病理观察  

Pleuropulmonary blastoma of adults： a clinicopathological analysis

作　　者：廖秋林[1] 彭大云[1] 田野[1] 

机构地区：[1]广州军区广州总医院病理科,510010

出　　处：《中华医学杂志》2010年第45期3203-3206,共4页National Medical Journal of China

摘　　要：目的 提高对成人胸膜肺母细胞瘤（PPB）病变的认识.方法 对2例PPB患者的临床、病理学特征及免疫组化表达进行详细的分析并复习相关文献.结果 发生于肺及胸膜的成人胸膜肺母细胞瘤是一种极其罕见的恶性间叶性肿瘤,起源于肺,胸膜或纵隔的原始间叶细胞,以胚胎性未分化肉瘤为特征,很难见到上皮,免疫组化间叶性抗体表达.结论 PPB是一种罕见的胚胎性恶性肿瘤,其特征性形态学改变不明显,免疫组化无特征性,临床病例少见,诊断比较困难.Objective To report two cases of pleuropulmonary blastoma （PPB） of adults and improving the understanding of this tumor.Methods The clinicopathological features of two cases of adult PPB were examined by light microscope and an immunohistochemical study.Results As a rare malignant mesenchymal tumor,PPB arose from primitive cells of lung,pleura and mediastinum.Consisting of primitive undifferentiated sarcoma cells and few epithelial cells,the tumor was positive for mesenchymal differentiated markers by immunohistochemistry.Conclusion PPB is a rare malignant embryonal tumor.The diagnosis of this tumor is rather difficult since it lacks pathomorphological or immunohistochemical features.

关 键 词：成人 胸膜肺母细胞瘤 肺母细胞瘤 

分 类 号：R686[医药卫生—骨科学]