痰浊内阻型冠心病的心率变异性分析以及与混沌理论的相关性研究  

A study on relativity between heart rate variability of cases with phlegm blocking type （痰浊内阻型） coronary heart disease and chaos theory

作　　者：冷永群[1] 李雪松[2] 涂婉华[1] 李超[1] 谢燕萍[3] 

机构地区：[1]武汉市中西医结合医院心功能科,湖北武汉430022 [2]武汉市中西医结合医院中医病房,湖北武汉430022 [3]武汉市中西医结合医院老年病科,湖北武汉430022

出　　处：《中国中西医结合急救杂志》2010年第6期340-342,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：基金项目：湖北省医药卫生科研基金项目[鄂卫函（2005）455号]

摘　　要：目的 探讨痰浊内阻型冠心病与混沌理论的相关性.方法 选择2008年3月至2010年3月本院心血管内科及中医病房住院的痰浊内阻型冠心病心绞痛患者60例（男29例,女31例）;同期本院门诊体检者70例（男32例,女38例）作为健康对照组.采用监测动态心电图中心率变异性（HRV）分析技术进行HRV分析,观察不同性别患者及健康人24 h NN间期标准差（SDNN）、5 min NN间期标准差（SDNN5）、相邻NN间期差值超过50 ms的心搏次数占NN间期总心搏次数的百分比（PNN50）、NN间期平均值的标准差（SDANN）、相邻NN间期差的平方根（RMSSD）、窦性R-R间期总个数除以R-R间期直方图高度得出的三角指数（TRIA）及夜间心率的变化.结果 痰浊内阻型冠心病组SDANN、TRIA明显低于健康对照组[SDANN（ms）：87.9±28.6比107.2±38.6,TRIA：445.5±157.6比523.1±170.4,均P〈0.01],其中以男性人群中SDANN（ms：93.8±29.1比113.7±39.4）降低较为显著,女性人群中SDNN（ms：123.5±43.6比144.3±38.2）、SDANN（ms：82.1±27.5比102.0±37.6）、TRIA（399.7±153.0比507.5±148.1）降低较为显著（P〈0.05或P〈0.01）.结论 痰浊内阻型冠心病与混沌理论存在相关性.Objective To study the relativity between phlegm blocking type （痰浊内阻型） coronary heart disease and chaos theory. Methods Sixty hospitalized patients （male 29, female 31） with angina pectoris of phlegm blocking type coronary heart disease in Vasculocardiology and Traditional Chinese Medicine Wards during March 2008 to March 2010 were enrolled in this study as the cardiac disease group~ 70 healthy cases （male 32, female 38）from Physical Examination Clinic during the same period were included in the control group. The heart rate variability （HRV） was analyzed from the data collected from dynamic monitor of electrocardiogram, and the changes in standard deviation of normal to normal intervals （SDNN）, standard deviation of normal to normal intervals in 5 minutes （SDNN5）, percentage of normal to normal 50% （PNN50）, standard deviation of the averages of normal sinus to normal sinus intervals in all 5-minute segments of a 2±hour recording （SDANN）, root mean square of successive differences （RMSSD）, heart rate variability triangular index （TRIA） change and heart rate change during the night between patients of different sexes and healthy people were observed. Results The SDANN and TRIA in phlegm blocking type coronary heart disease group were obviously lower than those in control group [SDANN （ms）： 87.9±28.6 vs. 107.2± 38.6, TRIA： 445.5± 157.6 vs. 523.1±170.4, both P〈O. 01]. The statistical differences were significant in the SDANN （ms： 93.8±29.1 vs. 113.7±39.4） in male patients, and in SDNN （ms： 123.5±43.6 vs. 144. 3± 38. 2） , SDANN （ms： 82.1±27.5 vs. 102.0±37.6） andTRIA （399.7±153.0vs. 507.5±148.1） in female patients （P〈0.05 or P〈 0.01）. Conclusion There is relativity between phlegm blocking type coronary heart disease and the theory of chaos.

关 键 词：混沌理论 心率变异性 冠心病心绞痛 痰浊内阻 

分 类 号：R256.1[医药卫生—中医内科学] R241.3[医药卫生—中医学]