以蓖麻油酸为原料合成1,9-壬二酸工艺的改进  

Improvement of 1,9-azelaic acid synthesis using castor oil acid as raw material

作　　者：赵玛[1] 杨萌萌[2] 刘大勇[2] 

机构地区：[1]郑州轻工业学院河南省表界面科学重点实验室,河南郑州450002 [2]黄淮学院化学化工系,河南驻马店463000

出　　处：《郑州轻工业学院学报（自然科学版）》2010年第5期65-67,共3页Journal of Zhengzhou University of Light Industry:Natural Science

基　　金：国家自然科学基金项目(50872069)

摘　　要：以自制的蓖麻油酸为原料,用高锰酸钾氧化法来制备1,9-壬二酸,采用单因素实验法探讨了反应条件对1,9-壬二酸收率的影响.获得的适宜反应条件为:n(KMnO4)∶n(蓖麻油酸)=3.5∶1,反应温度60～70℃,反应时间0.35h.该条件下,1,9-壬二酸的收率在95%以上.与其他的合成工艺相比,该工艺具有原料廉价易得、反应条件温和、产品收率高且纯度高等优点.1,9-azelaic acid was prepared by potassium permanganate method using self-made castor oil acid as raw material.The effects of reaction conditions were studied through single factor experiment.The optimum reaction conditions were obtained n（KMnO4）∶n（castor oil acid）=3.5∶1,reaction temperature 60~70 ℃,reaction time 0.35 h.The yield of 1,9-azelaic acid was over 95% under the optimum conditions.Compared with the old synthetic technology,the process has advantages such as cheap raw materials,moderate reaction conditions,high yield and high purity.

关 键 词：1 9-壬二酸 蓖麻油酸 高锰酸钾氧化法 

分 类 号：Q949.95[生物学—植物学]