外阴阴道白假丝酵母菌病发病机制及治疗进展  

Progress in research on pathogenesis and treatment of vulvovaginal candidiasis caused by Candida albicaus

作　　者：肖虹[1] 吴立涛[1] 祁文瑾[1] 

机构地区：[1]昆明医学院第一附属医院产科,云南昆明650032

出　　处：《中国妇幼健康研究》2010年第6期837-838,855,共3页Chinese Journal of Woman and Child Health Research

基　　金：国家自然科学基金资助项目（30760265）

摘　　要：外阴阴道假丝酵母菌病是较常见的妇女外阴阴道炎症之一,其主要致病菌是白假丝酵母菌.目前,白假丝酵母菌性阴道炎发病机制尚未完全阐明,主要归因于宿主与致病菌两方面的因素.由于抗真菌药物的长期大量使用,白假丝酵母菌对传统抗真菌剂耐药性逐渐增强,因此,有关新型抗真菌药物及生态疗法的研究,对减少白假丝酵母菌耐药性及传统抗真菌药物毒性具有重要临床意义.Vulvovaginal candidiasis （VVC） is a common infective disease in vulvus and vagina of woman. Candida albicans is the dominant species that causes VVC. For vaginitis caused by Candida albicans, decrease in host defense and virulence of Candida albicans are considered as the major pathogeneses of the disease. Because long term and high dose use of antimycotics,resistance of Candida albieans to conventional antimyoeoties becomes more and more stronger, so the study on new antimyeotics and ecological treatment may be helpful for reducing resistance of Candida albicans to conventional antimycoties and toxicity of the drugs.

关 键 词：外阴阴道假丝酵母菌病 发病机制 抗真菌药物 生态疗法 

分 类 号：R711.31[医药卫生—妇产科学]