多巴胺改性聚丙烯酸酯的合成及性能研究  

Synthesis and properties of dopamine modified polyacrylate

作　　者：张峰[1,2] 刘四委[1,2] 张艺[1,2] 许家瑞[1,2] 

机构地区：[1]聚合物复合材料及功能材料教育部重点实验室中山大学化学与化学工程学院,广东广州510275 [2]新型聚合物材料设计合成与应用广东省高校重点实验室中山大学化学与化学工程学院,广东广州510275

出　　处：《材料研究与应用》2010年第4期711-715,共5页Materials Research and Application

基　　金：国家自然科学基金(50903096和50873116);广东省自然科学基金(9451027501002566)

摘　　要：本文将海洋贻贝黏附蛋白中的黏附功能单元——多巴胺(Dopamine)接枝到聚丙烯酸酯上,从而得到了高性能的可降解的贻贝仿生聚丙烯酸酯.首先,将丙烯酸和丙烯酸正丁酯通过自由基聚合合成了聚丙烯酸-丙烯酸正丁酯共聚物;然后,利用1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐(EDC·HCl)将多巴胺接枝到聚丙烯酸酯上,制备了含多巴胺的贻贝仿生聚丙烯酸酯.通过其核磁共振(NMR)谱图确证了多巴胺成功地引入到了聚丙烯酸酯上.拉伸强度测试分析表明,引入多巴胺后的丙烯酸酯比原丙烯酸酯粘接性得到了大幅度提高,从0.053MPa提高到了0.124MPa,提高幅度达2倍多.静态水接触角的分析表明,引入多巴胺后,增强了丙烯酸酯的亲水性.此制备方法简单易行,可用于各种丙烯酸酯胶黏剂改性修饰.In this work,we grafted polyacrylate with a functionality of adhesive proteins in mussels,3,4-dihydroxyphenylalanine（DOPA）,to obtain a mussel-mimic and biodegradable polyacrylate with high-performance. Firstly,poly （acrylate-co-N-butyl acrylate） was synthesized with acrylate and N-butyl acrylate via free radical polymerization; then dopamine was grafted to poly （acrylate-co-N-butyl acrylate） in the presence of N-（3-dimethylaminopropyl）-N-ethylcarbodiimide hydrochloride（EDC·HCl）. The product was characterized by NMR,which confirm that dopamine was grafted in the polymer. Analysis of tensile strength test revealed the adhesive was improved of up to 2 times after polyacrylate was modified with dopamine,from 0.053 MPa to 0.124 MPa. Analysis of the static water contact angle suggested that,after it was grafted with dopamine,the hydrophilic of polyacrylate was inhanced. This method is ease of application and capacity for modification of varied acrylic adhesive.

关 键 词：多巴胺 聚丙烯酸酯 贻贝仿生 降解 

分 类 号：O632.52[理学—高分子化学]