病态造血在骨髓增生异常综合征中的特点及诊断价值  

Dysplasia in myelodysplastic syndrome and diagnostic value of features

作　　者：张红梅[1] 

机构地区：[1]河南大学淮河医院检验科,河南开封475000

出　　处：《中国当代医药》2010年第34期86-87,共2页China Modern Medicine

摘　　要：目的：分析病态造血在骨髓增生异常综合征（MDS）中的特点及诊断价值。方法：收集2004年5月~2009年10月以2001年世界卫生组织（WHO）MDS分型标准[1]为诊断标准的MDS102例,分别进行骨髓细胞学检查,外周血涂片检查。结果：MDS特征性形态学诊断依据,粒系为Auer小体,双核粒细胞,微核;红系为奇数核及核出芽;巨核系为淋巴样小巨核;外周血片出现原始粒细胞及巨核细胞。结论：细胞形态学是MDS的重要基础诊断手段。诊断早期的MDS需结合其他的检测技术以提高MDS诊断的准确率。Objective：To investigate the characteristics and diagnosis value of dysplasiain myelodysplastic syndrome.Methods：102 samples with MDS were collected between May 2004 and September 2009.Based on the diagnostic standard of WHO MDS classification,all cases were detected on bone marrow pathological assay,peripheral blood cytomorphology.Results：The characteristic cytomorphological diagnosis basis of MDS could be：granular Auer bodies,binuclear granular cell,micronucleus;erythroid nuclear budding or the odd number nucleus;micronucleus was the lymphoid small micronucleus;myeloblast or megakaryocytes in peripheral blood.Conclusion：Cytomorphologic assay was the important basis for the diagnosis of MDS,other detection methods is required for enhance the rate of accuracy in the early diagnosis of MDS.

关 键 词：病态造血 综合征 骨髓增生异常 

分 类 号：R551.3[医药卫生—血液循环系统疾病]