复方芪术汤对脾虚型艾滋病患者中医证候的疗效及外周血CD4 T淋巴细胞的影响  

Effects of "Fufang Qizhu Decoction" on Spleen-deficiency Syndrome and CD4 T Lymphocytes of AIDS Patients

作　　者：陈晓蓉[1] 杨宗国[1] 沈芳[1] 王江蓉[1] 卢洪洲[1] 巫善明[1] 

机构地区：[1]上海市公共卫生临床中心中医科,上海201508

出　　处：《上海中医药大学学报》2010年第6期40-42,共3页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：上海颜德馨中医药基金会资助项目(05-010)

摘　　要：目的:观察复方芪术汤对脾虚型艾滋病患者脾虚证候的疗效及外周血CD4 T淋巴细胞的影响。方法:43例伴有脾虚证的艾滋病患者随机分为治疗组(n=21)和对照组(n=22)。治疗组采用复方芪术汤联合HAART治疗,对照组单纯采用HAART治疗,疗程均为6个月。观察两组患者治疗前后中医证候及外周血CD4 T淋巴细胞水平的变化。结果:治疗组总有效率为90.0%,对照组总有效率为60.0%,两组总有效率比较差异有统计学意义(P<0.05)。治疗后,两组患者的CD4 T淋巴细胞水平均较治疗前明显提高(P<0.05),治疗组CD4 T淋巴细胞水平较对照组亦显著提高(P<0.05)。结论:复方芪术汤不仅可有效改善脾虚型艾滋病患者的脾虚证候,而且可明显提高患者的细胞免疫水平。Objective： To observe the effects of ＂Fufang Qizhu Decoction＂ on spleen-deficiency syndrome and CD4 T lymphocytes of patients with acquired immune deficiency syndrome（AIDS）.Methods： Forty-three cases of AIDS with spleen-deficiency syndrome were randomly divided into treatment group（n=21） and control group（n=22）.The treatment group was treated by ＂Fufang Qizhu Decoction＂ combined with highly active antiretroviral therapy（HAART） and the control group was treated by HAART only.After treatment of 6 months,the clinical effects and the level of CD4 T lymphocytes were observed.Results： The clinical effective rates of treatment group and control group were 90.0% and 60.0% respectively and there was a statistical difference between the two groups（P0.05）.The levels of CD4 T lymphocytes of both two groups after treatment were higher than those before treatment（P0.05）and the level of CD4 T lymphocytes in treatment group was higher than those in control group after treatment（P0.05）.Conclusion： ＂Fufang Qizhu Decoction＂ can improve the spleen-deficiency syndrome of AIDS patients and enhance the level of cellular immunity.

关 键 词：复方芪术汤 艾滋病 脾虚证 CD4 T淋巴细胞 

分 类 号：R259[医药卫生—中西医结合]