半夏白术天麻汤4种提取液对高血压痰湿壅盛型大鼠的影响  

Effects of Four Kinds of Extract of Banxia Baizhu Tianma Decoction on Hypertensive Rat with Abundant Phlegm-dampness

作　　者：王淑玲[1] 孙秀梅[2] 张兆旺[2] 谢恬[1] 

机构地区：[1]杭州师范大学生物医药与健康研究中心,杭州310012 [2]山东中医药大学药学院,济南250014

出　　处：《中国实验方剂学杂志》2010年第18期179-182,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:用主要药效学实验验证半夏白术天麻汤用优选的半仿生-生物酶法(SBEE法)提取工艺进行提取的科学性和合理性。方法:建立高血压痰湿壅盛型大鼠模型,对半夏白术天麻汤4种方法提取液(SBEE法、SBE法、WE法、AE法)作对模型大鼠的11个指标影响的比较。结果:半夏白术天麻汤对高血压痰湿壅盛型大鼠的11个指标的影响,以SBEE法提取液综合评价RA值最大,分析半夏白术天麻汤提取方法以SBEE法效果较好。结论:半夏白术天麻汤以SBEE法提取为佳。Objective：To validate the scientific rationality of optimized extraction technics for Banxia Baizhu Tianma decoction in SBEE experiment with main efficacy as indicators.Method：Rat model of hypertension with abundant phlegm-dampness was estabilished.Eleven indicators closely associated with abundant phlegm-dampness were selcted for evaluating effects.indicators closely associated with abundant phlegm-damphess.Four kinds of solution of Banxia Baizhu Tianma decoction（SBEE,SBE,WE,AE） were compared for their effectiveness. Result：Effects on the hypertensive rat showed that SBEE solution had the best effect. Conclusion： SBEE is the best extracting method for Banxia Baizhu Tianma decoction.

关 键 词：半夏白术天麻汤 半仿生-生物酶法 高血压痰湿壅盛型 

分 类 号：R285.5[医药卫生—中药学]