非变应性鼻炎与变应性鼻炎临床特点初步分析  

Clinical characteristics in patients with non-allergic rhinitis and allergic rhinitis：preliminary analysis

作　　者：孟粹达[1] 李琳[1] 姜晓丹[1] 董震[1] 朱冬冬[1] 

机构地区：[1]吉林大学中日联谊医院耳鼻咽喉头颈外科,长春130033

出　　处：《中华耳鼻咽喉头颈外科杂志》2010年第12期999-1002,共4页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：国家“十一五”科技攻关项目（2007CB516706）;卫生部临床学科重点项目（07090138）

摘　　要：目的 探讨高反应性非变应性鼻炎（hyperreactivity non-allergic rhinitis,HNAR）与变应性鼻炎（allergic rhinitis,AR）在性别、年龄分布、发病季节、诱因及临床表现的差异.方法 选择2009年1-8月398例以高反应性鼻部症状首诊的诊断为HNAR及AR的连续患者,以SPSS 17.0软件对其性别、年龄、发病季节、分型、诱发因素及临床症状等因素进行统计分析.结果 HNAR与AR的性别分布差异有统计学意义（χ2=6.415,P=0.01）,HNAR女性患者居多,AR以男性为主;在发病年龄上,HNAR以中青年为主,高发年龄在30～39岁（χ2=51.533,P=0.00）,AR以青少年为主,高发年龄在10～19岁（χ2=12.772,P=0.00）;HNAR发病无明显季节性,AR发病多在秋季.AR变应原以艾蒿和豚草为主.AR以中-重度持续性为主（χ2=123.991,P=0.00）,HNAR以中-重度间歇性为主（χ2=97.420,P=0.00）;除鼻痒外,AR较HNAR鼻部及眼部的临床症状重（P值均〈0.05）;非特异性诱发因素在AR与HNAR患者发病过程中的作用大致相似（统计值,P〉0.05）.结论 AR与HNAR在性别构成、主要发病年龄、鼻炎分型及发病季节上有明显差异,除鼻痒外AR鼻部及眼部临床症状较HNAR重,但在发病诱因上呈一致性.Objective To compare and analyze the clinical characteristics in patients with hyperreactive non-allergic rhinitis （HNA R） and allergic rhinitis （AR）. Methods A questionnaire survey on AR and HNAR patients between January and August 2009 was conducted. The clinical data of 298 AR patients and 100 HNAR patients were analyzed, including gender, age distribution, seasonal, clinical symptom and induced factors. Results The number of male patients was more than female in AR, while in NAR, the number of female patients was more than male（χ2 =6. 415, P =0. 01）. The highest morbidity age in AR was teenagers, aged between 10 - 19 （χ2 = 12. 772, P = 0. 00）, while in HNAR, the highest morbidity age was middle-aged and youth, aged between 30-39（χ2 =51. 533, P =0. 00）. The main onset seasons in AR was autumn, while there was no seasonal diversity in HNAR. The main allergen in AR was mugwort and ragweed, consistent with the vegetative cover characteristic in Jilin province. The main classification of AR was moderate-severe persistent（χ2 = 123.991, P =0. 00）, while the main classification of HNAR was moderate-severe intermittent （χ2 = 97. 420, P = 0. 00） . The clinical symptoms were significantly different between AR and HNAR except rhinocnesmus（all P 〈 0. 05）. There was consistency about non-specificity induced factors in AR and HNAR（all P 〉 0. 05）. Conclusions There were significant differences between AR and HNAR in sex, age, classification and seasons. The severity of clinical symptoms in AR was higher than that in HNAR except sneezing and gasping. There was consistency about induced factors in AR and HNAR.

关 键 词：鼻炎 变应性 季节性 鼻炎 变应性 常年性 鼻炎 血管运动性 鼻炎 非变应性 

分 类 号：R686[医药卫生—骨科学]