血浆血浆纤维蛋白原和D一二聚体检测对老年髋部骨折术后并发深静脉血栓的早期诊断价值  

作　　者：黎文武[1] 李建生[1] 卢小燕[1] 蔡玉明[1] 廖育军 邓月香[1] 徐昆[1] 刘艳凤[1] 

机构地区：[1]广东省广州市白云区人民医院外2区,510500

出　　处：《医学信息（下旬刊）》2010年第12期58-58,共1页Medical information

摘　　要：目的：探讨血浆血浆纤维蛋白原（fg）及D一二聚体（D-Dimer DD）检测对老年髋部骨折术后并发深静脉血栓（DVT）的早期诊断价值.方法：对186例老年髋部骨折患者术前及术后第3、7天进行血浆血浆纤维蛋白原（fg ）及D一二聚体的定量检测,跟踪观察患者病情.结果：186例患者有18例并发DVT,并发DVT组术前、术后第3、7d血浆纤维蛋白原（fg ）及D一二聚体的检测结果有显著性差异（P＜0.05）.未并发DVT组术前、术后第3、7天血浆纤维蛋白原（fg）及D一二聚体的检测结果无显著性差异（P＞0.05）.而并发DVT组与未并发DVT组相比较：术前血浆血浆纤维蛋白原（fg）及D一二聚体的检测结果无显著性差异（P＞0.05）;术后第3、7d血浆血浆纤维蛋白原（fg）及D一二聚体的检测结果有显著性差异（P＜0.05）.结论：血浆血浆纤维蛋白原（fg）及D一二聚体的动态监测对老年髋部骨折并发DVT具有早期诊断价值.Objective The aim of this study was to discuss early d：agnostic value of plasma fibrinogen and D-dimer assay in deep vein thrombosis （DVT）after elderly hip fracture. Methods Quantitively detect plasma fibrinogen and D-dimer in 186 patients with elderly hip fracture during the phases preoperative and 3,7 days postoperative,and follow up the patients conditions. Results 18 patients occur deep veinthrombosis. The different level of plas- ma fibrinogen and D--dimer during the phases preoperative and 3,7 days postoperative in DVT group was significant （P〈0.05）. The different level of plasma fibrinogen and D--dimer during the phases preoperative and 3.7 days Postoperative in NO DVT group was not significant （P〉0.05）. The differ- ent level of plasma fibrinogen and D--dimer between two groups： preoperative was not significant（P〉 0.05） ,3 .7 days postoperative was significant （P〈0.05）. Conclusion Dynamic determination of plasma fibrinogen and D--dimer is very useful for predicting occurrence of thromboembolism in elderly hip fracture.

关 键 词：D一二聚体 老年髋部骨折 DVT 

分 类 号：R683.4[医药卫生—骨科学]