妊娠期异位蜕膜42例临床病理分析  

The Clinicopathologic Analysis of 42 Patients with Ectopic Decidua in Gestation Period

作　　者：王丽琼 刘大刚 杨芳 朱惠荣 

机构地区：[1]昆明市延安医院病理科,云南昆明650051

出　　处：《昆明医学院学报》2010年第11期127-129,共3页Journal of Kunming Medical College

摘　　要：目的探讨妊娠期异位蜕膜的临床及病理表现.方法对42例正常妊娠和异位妊娠的异位蜕膜临床资料进行回顾性分析.结果异位蜕膜为鲜红色结节,可见于大网膜、宫颈及后穹隆等部位;光镜下异位蜕膜细胞多边形镶嵌状排列,胞浆丰富,核位于细胞中央;免疫组化显示Vimentin、EMA、PRL、ER及PR呈阳性表达,CK、LCA、SMA、desmin和actin呈阴性表达.结论妊娠期在大网膜、宫颈及后穹隆等部位可以发生异位蜕膜,临床易误诊为肿瘤,免疫组织化学可辅助诊断和鉴别诊断;提高对异位蜕膜的认识十分必要.Objective To study the clinicopathologic manifestations of ectopic decidua in gestation period.Method The clinical data of ectopic deciduas of 42 cases including normal and ectopic pregnancy were analyzed retrospectively.Results Ectopic deciduas were bright red nodules which could be seen in great epiploon,cervix and postfornix under light microscope,the ectopic decidual cells with rich cytoplasms were polygonal and inlaid arrangement,nucleus laid in the center of cells.Immunohistochemistry：ectopic decidual cell expressed Vimentin,EMA,PRL,ER and PR,but did not express CK,LCA,SMA,Desmin and Actin.Conclusions During gestation period,the ectopic decidua can happen in cervix,ovary,great epiploon,vagina and so on,which is easy to be misdiagnosed as tumor,immunohistochemistry can help to diagnose and differentiate.It is necessary to improve the recognition of ectopic decidua.

关 键 词：异位蜕膜 蜕膜反应 妊娠 免疫组化 

分 类 号：R714.2[医药卫生—妇产科学]