96例胆囊癌的外科治疗与预后因素分析  

Surgical treatment and prognosis of gallbladder carcinoma in 96 cases

作　　者：王越[1] 葛春林[1] 张军[1] 葛金年[1] 高君[1] 罗蓟[1] 

机构地区：[1]中国医科大学附属第一医院普通外科教研室肝胆外科,沈阳110001

出　　处：《中华肝胆外科杂志》2010年第11期828-830,共3页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的 研究影响胆囊癌预后的因素.方法 回顾性分析中国医科大学附属第一医院1993-2003年收治的96例胆囊癌临床资料并进行预后多因素Cox回归模型分析.结果 胆囊癌的总体5年生存率为6.32%,胆囊癌根治切除组的1、3、5年生存率分别为78.36%、48.54%和23.87%,与姑息手术组、剖腹探查组、非手术组间之间的差异有统计学意义;Cox模型多因素分析表明手术方式和肿瘤的浸润深度与胆囊癌的预后显著相关,其中手术方式为保护性因素.结论 早期诊断并予根治是胆囊癌病人长期生存的保证,适宜的围手术期处理有助于改善生存率.Objective To study parameters influencing the prognosis of patients with gallbladder carcinoma.Methods A retrospective clinical analysis was conducted in 96 cases of gallbladder carcinoma treated in this hospital between 1993 and 2003.Results The overall 5-year survival rate of the patients was 6.32%.The 1-, 3-, and 5-year survival rates following radical resection for gallbladder carcinoma were 78.36%, 48.54%, and 23.87%, respectively.The survival rate was remarkably higher in the radical resection group than in others.Multivariate analysis revealed that depth of infiltration of the tumor and surgical procedure were markedly associated with prognosis.Conclusion Early diagnosis and radical resection are still the mainstay for long-term survival of the patients with gallbladder carcinoma.Appropriate perioperative care can improve survival rate.

关 键 词：胆囊肿瘤 外科手术 预后因素 

分 类 号：R686[医药卫生—骨科学]