主动脉瓣钙化与冠心病有关联  

Association between aortic valve calcification and coronary artery disease

作　　者：龚东[1] 楼建英[2] 彭健[1] 张伟[2] 王达理[2] 钱维源[2] 

机构地区：[1]中山大学附属第五医院心内二科,广东珠海519000 [2]解放军第四五四医院心内科,江苏南京210002

出　　处：《心脏杂志》2010年第6期922-924,共3页Chinese Heart Journal

摘　　要：目的:探讨中国南方部分汉族人群主动脉瓣钙化与冠心病之间的关系。方法:选取同期行冠状动脉造影检查和超声心动图检查患者1 153例,探讨主动脉瓣钙化与冠心病的相关性。结果:冠心病组主动脉瓣钙化的检出率明显高于非冠心病组(32.6%vs.13.9%,P<0.01),多因素Logistic回归分析结果显示,除传统危险因素如年龄、性别、高脂血症、糖尿病外,主动脉瓣钙化也是全组冠心病的一项独立的预测因子(OR=1.53,P<0.05)。结论:主动脉瓣钙化与全组冠心病发病之间存在显著的相关性,是冠心病的一项有意义的独立预测因子。AIM： To determine the relationship between aortic valve calcification （AVC） and coronary artery disease （CAD） in part of the Han population in southern China. METHODS： Enrolled in the study were 1 153 subjects who underwent both transthoraeic echocardiography （TTE） and coronary arteri- ography （CAG）, and the relationship between aortic valve calcification （AVC） and CAD was explored. RESULTS： The prevalence of AVC was significantly higher in the CAD group compared with that in non-CAD group （32.6% vs. 13.9%, P 〈0. 01 ）. Multiple logistic regression analysis showed that in addition to age, gender, diabetes mellitus and hyperlipidemia （all P 〈 0.01 ）, AVC （P 〈0.05） was an independent positive predictor of coronary arteriography. CONCLUSION： There is a significant association between the presence of AVC and CAD. Aortic valve calcification is an independent predictor of CAD.

关 键 词：主动脉瓣钙化 冠状动脉疾病 动脉粥样硬化 超声心动描记术 冠状动脉造影术 

分 类 号：R541.4[医药卫生—心血管疾病]