氨酚羟考酮片平衡镇痛在急诊创伤患者中的应用  

Balance analgesic efficacy of oxycodone and acetaminophen tablets in management of trauma pain in emergency room

作　　者：李连华[1] 孙天胜[1] 刘智[1] 任大江[1] 黄炎[1] 陈晓斌[1] 

机构地区：[1]北京军区总医院全军创伤骨科研究所,北京100700

出　　处：《中国新药杂志》2010年第23期2161-2164,共4页Chinese Journal of New Drugs

摘　　要：目的:研究氨酚羟考酮片在急诊创伤患者中应用的临床效果。方法:前瞻性随机选取156例患者,根据疼痛程度VAS≥7(10)分患者每6 h服用2片,VAS<7(10)分患者每6 h服用1片,在服药1 h后评估治疗前后疼痛缓解程度和不良反应的发生情况。结果:服用氨酚羟考酮片总有效率为78.8%,软组织挫伤、皮肤裂伤及关节扭伤镇痛效果要优于骨折镇痛的效果。在不良反应方面,胃肠道反应常见,耐受性较好。结论:氨酚羟考酮片治疗急诊创伤患者可有效缓解疼痛,安全有效。Objective： To evaluate the efficacy and adverse effects of oxycodone acetaminophen tablets in patients with trauma pain in emergency room.Methods： A total of 156 patients with trauma pain were treated with oral oxycodone acetaminophen tablets.All patients were asked to record the visual analogue scales of pain and adverse effects of the treatment.Results： Oxycodone acetaminophen tablets showed a good analgesic efficacy in the treatment of trauma pain in emergency room.The overall effective rate after one hour was 78.8%.The effect on soft tissue contusion,skin laceration and joint sprain was better than that on bone fracture.The common adverse effects included constipation,nausea and vomiting,which were well tolerated.Conclusion： Oxycodone acetaminophen tablets are effective,safe,and convenient in patients with trauma pain in emergency room.

关 键 词：氨酚羟考酮片 急诊 创伤 疼痛 

分 类 号：R971[医药卫生—药品]