针刺结合饮食调整及有氧运动对单纯性肥胖症患者体重、体重指数及血清瘦素含量的影响  

Effects of Acupuncture Combined with Dietary Adjustments and Aerobic Exercise on Body Weight,Body Mass Index and Serum Leptin Level in Simple Obesity Patients

作　　者：杨继军[1] 邢海娇[1] 王少锦[1] 肖红玲[1] 李梅[2] 李青[3] 

机构地区：[1]河北医科大学中医学院针灸系,石家庄050091 [2]河北省中医院针灸科,石家庄050017 [3]石家庄市中心医院中医科,石家庄050017

出　　处：《针刺研究》2010年第6期453-457,共5页Acupuncture Research

基　　金：河北省中医药管理局科技攻关课题基金资助(2007028);河北省科技厅科技支撑计划项目(08276101D-95)

摘　　要：目的:观察针刺结合饮食调整及有氧运动对单纯性肥胖症的影响,并探讨其作用的相关机制。方法:61例单纯性肥胖症患者随机分为对照组和治疗组。对照组采用饮食调整及有氧运动进行减肥,连续51 d。治疗组在进行饮食调整和有氧运动的基础上,针刺中脘、天枢、关元、足三里、丰隆、阴陵泉、三阴交、脾俞、胃俞等腧穴,15次为1个疗程,疗程间隔3 d,共3个疗程。患者称重后,计算体重指数(BMI);采用放射免疫法测定血清瘦素(Lep)含量。结果:两组治疗前后比较,体重、BMI、血清Lep含量均明显降低(P<0.01)。治疗组体重分别在第1疗程、第3疗程后均低于对照组(P<0.05);BMI在各个疗程后均明显低于对照组(P<0.05,P<0.01);Lep含量治疗后明显低于对照组(P<0.05)。治疗前后差值比较,治疗组体重及BMI均明显大于对照组(P<0.01)。结论:针刺结合饮食调整及有氧运动可降低单纯性肥胖症患者的体重、BMI、血清Lep含量,且作用优于单纯饮食调整及有氧运动。Objective To observe the effect of acupuncture combined with dietary adjustments and aerobic exercise on the body weight, body mass index （BMI） and serum leptin content of patients with simple obesity, so as to evaluate the efficacy of the present therapy in the treatment of simple obesity. Methods A total of 61 cases of out-patients were randomly divided into control （n = 30） and treatment （n = 31 ） groups. Patients in the control group were treated with dietary adjustments and aerobic exercise everyday （30 min/d）, continuously for 57 days, and those of the treatment group were treated with acupuncture [Zhongwan （CV 12）, Tianshu （ST 25）, Guanyuan （CV 4）, etc. ] plus dietary adjustment and aerobic exercise everyday, with 15 days being a course of treatment, 3 days＇ interval between every two courses, and 3 courses altogether. Serum leptin content was detected by using radioimmunoassay. Ressults Compared with pre-treatment, the body weight and BMI and serum leptin levels in the control and treatment groups were all decreased significantly （P〈0.01）. Comparison between the two groups showed that the body weight at the end of the 1^st and 3^rd course of treatment, the BMI at the end of the 1^st , 2^rd and 3^rd course of treatment, and serum leptin level after the treatment in the treatment group were all significantly lower than those in the control group （ P〈0.05, P〈0.01 ）. The difference values of body weight and BMI between pre-treatment and post-treatment of the treatment group were obviously higher than those of the control group （P〈0.01）, suggesting a better therapeutic effect of acupuncture combined with dietary adjustments and aerobic exercise in the treatment of simple obesity. Conclusion Acupuncture combined with dietary adjustments and aerobic exercise can reduce the body weight, BMI and serum leptin level, which is better than dietary adjustments plus aerobic exercise.

关 键 词：单纯性肥胖症 针刺 饮食调整 有氧运动 体重 体重指数 血清瘦素 

分 类 号：R589.2[医药卫生—内分泌]