马拉色菌属的研究进展  

Study Progress of Malassezia

作　　者：拓江[1] 路永红[1] 

机构地区：[1]成都市第二人民医院(遵义医学院附属成都医院)皮肤科,四川成都610017

出　　处：《中国皮肤性病学杂志》2011年第1期66-68,共3页The Chinese Journal of Dermatovenereology

基　　金：成都市医学重点学科基金资助(成卫科教【2007】44号)

摘　　要：马拉色菌是一种寄生于人和动物正常皮肤表面的真菌,可导致机会感染而引起各种马拉色菌属相关疾病。马拉色菌的致病机制主要是分解脂质,导致角质形成细胞形态学改变和细胞凋亡。马拉色菌可引起花斑癣、脂溢性皮炎、马拉色菌毛囊炎等,在特应性皮炎中也起到变应原的作用。对于这些疾病的治疗可使用抗真菌药物。Malassezia is a sort of parasitic fungus in the surface of normal skin of humans and animals, it can lead to opportunistic infections and cause a variety of Malassezia-related diseases. Malassezia can decompose lipids, and result in morphological changes of keratinocytes and apoptosis, which is its main etiological factor. Malassezia can cause pityriasis versicolor, seborrheic dermatitis, Malassezia folliculitis, etc. In atopic dermatitis, it may play a role as allergen. For the treatment of these diseases , antifungal medicine can be used.

关 键 词：马拉色菌属 致病因素 花斑癣 马拉色菌毛囊炎 脂溢性皮炎 特应性皮炎 

分 类 号：R379[医药卫生—病原生物学] R756[医药卫生—基础医学]