高血压患者肾微循环功能障碍与冠状动脉病变相关研究  

The relationship of renal microcirculation dysfunction and severity of coronary artery stenosis in essential hypertension patients

作　　者：刘卫华 黄群英 庞振瑶 

机构地区：[1]广西桂林第二人民医院心内科,桂林541001

出　　处：《陕西医学杂志》2010年第12期1611-1613,共3页Shaanxi Medical Journal

摘　　要：目的:探讨高血压患者肾微循环功能障碍与冠状动脉病变程度的关系。方法:180例高血压患者分别测定尿微量白蛋白(mALB)、β2-微球蛋白尿(β2-MG)、血尿酸(UA)、血清胱抑制素C(CysC),根据结果分为有肾微循环障碍组和非肾微循环障碍组。比较两组冠状动脉病变支数严重程度。结果:有肾微循环障碍组冠状动脉狭窄率较非肾微循环障碍组高,且双支、多支病变更严重。结论:高血压患者肾微循环障碍与冠心病的发展有关,与冠状动脉病变程度有正相关。Objective：To analysis the relationship of renal microcirculation disturbance and the coronary artery stenosis degree in essential hypertension patients.Methods： Patients were categorized two groups （the renal microcirculation disturbance group and the non renal microcirculationdisturbance group）,which based on the results of mAlb /UA/CysC/β2-MG. The resuvt of the coronary artery stenosis degree was compared between the two groups.Results： The rate of coronary artery stenosis of the former group is higher than that in latter group, and double-branch, multi-vessel disease was more serious.Conclusion： The development of coronary heart disease are related to renal microcirculation disturbance on essential hypertension patients, the coronary artery stenosis degree associated with renal microcirculation .

关 键 词：高血压/并发症 @肾微循环功能障碍 冠状动脉疾病 白蛋白尿 尿酸/血液 

分 类 号：R544.1[医药卫生—心血管疾病]