新型1,4,5,8-萘酰亚胺类衍生物的合成  

Synthesis of Novel 1,4,5,8-Naphthalimide Derivatives

作　　者：刘万定[1] 吕良飞[1] 汪维[1] 陈梅[1] 唐超[1] 吴杰颖[1] 

机构地区：[1]安徽大学化学化工学院,安徽合肥230039

出　　处：《合成化学》2010年第6期709-711,共3页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金资助项目(20771001);安徽省教育厅重点科研项目(KJ2010A030)

摘　　要：以1,4,5,8-萘四甲酸二酐(1)和2-乙基己胺(2)为原料,设计并合成了3种新型的1,4,5,8-萘酰亚胺类衍生物,其结构经1H NMR,IR和MS表征。中间体N-(2-乙基己基)-萘-1,8-二甲酸单酐-4,5-单甲酰亚胺的最佳反应条件为:19.7 mmol,n(1)∶n(2)=1.1∶1.0,以醋酸锌为催化剂,在DMF(20 mL)中于140℃反应15h,收率25%。Three novel 1,4,5,8-naphthalimide derivatives were designed and synthesized from 1,4,5,8-naphthalenetetracarboxylic dianhydride（1） and 2-ethylhexan-1-amine（2）.The structures were characterized by 1H NMR,IR and MS.The optimum reaction conditions of synthesizing intermediate N-（2-ethylhexyl）-1,4,5,8-naphthalenetetracarboxylic-1,8-anhydride-4,5-imide were as follows： 1 was 9.7 mmol;n（1） ∶n（2） was 1.1 ∶1.0;Zinc acetate was used as the catalyst and the reaction carried out in DMF（20 mL） at 140 ℃ for 15 h.The yield was 25% under the optimum reaction conditions.

关 键 词：2-乙基己胺 萘酰亚胺 衍生物 合成 

分 类 号：O625.63[理学—有机化学] O621.3[理学—化学]