中国肾综合征出血热监测研究  

Study and surveillance of HFRS(Hemorrhage Fever with Renal Syndrome)in China

作　　者：陈化新[1,2,3,4,5,6,7,8,9] 罗成旺[1,2,3,4,5,6,7,8,9] 陈富 王锡怀[1,2,3,4,5,6,7,8,9] 杨建华 马立军 孙怀玉 姚兆华 邱季春 

机构地区：[1]中国预防医学科学院流行病学微生物学研究所 [2]太原市卫生防疫站 [3]北京市卫生防疫站 [4]高安市卫生防疫站 [5]户县卫生防疫站 [6]安庆市卫生防疫站 [7]天台县卫生防疫站 [8]临沂市卫生防疫站 [9]广州市卫生防疫站

出　　处：《中国公共卫生》1999年第7期616-623,共8页Chinese Journal of Public Health

基　　金：卫生部疾病控制司资助

摘　　要：自１９８４年以来，在我国３０个省（自治区、直辖市）由卫生部和中国预防医学科学院先后建立了４８个全国肾综合征出血热（ＨＦＲＳ）监测点（自１９９１年调整为４１个，即调下的有延边州、徐州市、镇江市、沛县、巩义市、平顶山市、成都市，调上的有蛟河市、大丰县、东海县、确山县、淮阳县、涪陵市）。并委托我所负责具体业务和有关监测研究工作。１４年来，通过ＨＦＲＳ监测点多年动态的人间疫情监测、宿主动物监测、疫源地和疫区监测和控制效果监测，以及自然科学基金课题（疫源地结构和传播机理研究）等内容的监测研究，并结合对全国范围的调查和实验室研究，取得了大量的科学数据。１９８４～１９９７年共检测血清２０３３７５人份。查证临床诊断病例血清学符合率，１９８４～１９９０年为８０３７％（９１５３／１１３８９）；１９９１～１９９７年为７２４４％（１１５１２／１５８９２）。１９８４～１９９０年疑似病例血清学符合率为４６５１％（１０９４２／２３５２７）；健康人群ＨＶ隐性感染率为２７６％（３８３８／１３９０６３）；３９０例ＨＦＲＳ恢复期病人血清学分型结果，姬鼠型占５３３０％，家鼠型占４１７７％，未定型占４９３％。１９８４～１９９０年检测Ｈ?Surveillance sopts of HFRS have been established in 30 provinces(or Autonomous regions and Municipal Cities)since 1984 by the Ministry of Public Health and Chinese Academy of Preventive Medicine.In 1991 these surveillance spots were adjusted to 41:Yanbian District,Xuzhou City,Zhenjiang City,Pei County,Gongyi City,Pingdingshan City and Chengdu City were canceled and Jiaohe City,Dafeng County,Donghai County,Queshan County,Huaiyang County and Fuling City were added.Our Institute was entrusted for in charge of the professional work and study of all these surveillance spots. During the 14 years we had the surveillance andstudy of HFRS trends on human epidemic situation,host animals,epidemic sources and areas,effect control;as well as the program of NSFC General Project(study on the structure of epidemic sources and areas and the spreading mechanisms),combined with the whole nationa′s investigation and laboratory research we got a large number of scientific data. From 1984 to 1997 we examined 203375 samples of human serum.Accordance of them with clinical diagnosis were as follows:80 37%(9153/11389) from 1984 to 1990 and 72 44%(11512/15892) from 1991 to 1997.From 1984 to 1990 we examined the serum samples of suspicious patients,the accordance of them with clinical diagnosis was 46 51%(10942/23527);the rate of recessive infection of HV in health people was 2 76%(3838/139063);the classification result of 390 serum samples from recovered patients showed that the virus type of Apodemus agrarius was 53 30%,the type of domestic mouse was 41 77% and the undefined type was 4 93%.Form 1984 to 1990 we also examined the double serum amples of 3144 patients,84 83% of them had 1∶320 IgG in 6th days of HFRS and 82 06% of them had 1∶320 titer of IgG during the recovered period.We examined the duration time of IgG after suffering from HFRS and the results showed that the duration time of IgG was from one month to 28 years.In 1991 to 1997 the rate of failing to report was fluctuated from 0 70% to 9 24% and the average

关 键 词：肾综合征出血热 监测 中国 

分 类 号：R512.801[医药卫生—内科学]