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作 者:廖瑜修[1]
机构地区:[1]广西中医学院附属瑞康医院,广西南宁530011
出 处:《中成药》2010年第12期2037-2040,共4页Chinese Traditional Patent Medicine
摘 要:目的:观察通心络胶囊治疗稳定型心绞痛的临床疗效。方法:选择稳定型心绞痛患者78例,随机分成2组。治疗组52例,基本治疗(单硝酸异山梨酯和阿司匹林)加用通心络胶囊治疗;对照组26例,单用基本治疗,35d为1个疗程,观察心绞痛疗效、心电图变化和血液流变学变化。结果:治疗组与对照组心绞痛总有效率分别为82.7%和57.7%;心电图总有效率分别为73.1%和46.2%;血液流变学改善,治疗组均优于对照组,比较2组差异有统计学意义(P<0.05或P<0.01),并无副反应。结论:通心络胶囊治疗稳定型心绞痛具有明显的临床疗效。AIM: To observe the clinical effect in the treatment of patients with stable angina pectoris by using Tongxinluo Capsule.METHODS: Seventy-eight patients with stable angina pectoris were randomly divided into two groups.The therapeutic group(n = 52) was treated with basic therapy(Isosorbide mononitrate + Aspirin) and Tongxinluo Capsule and the control group(n = 26) was treated with basic therapy.The changes of syndrome coroary artery disease and ECG and hemorheology were observed after one course of treatment(35 d).RESULTS: The total clinical effective rates in the therapeutic group were 82.7% and 57.7% in the control group respectively.The total ECG changes were 73.1% in the therapeutic group and 46.2% in the control group respectively.Hemorheology in the therapeutic group was better than that in the control group.There was a statistical difference between the two groups(P 〈 0.05 or P 〈 0.01).No adverse effect was found in the therapeutic group.CONCLUSION: Tongxinluo Capsule has obvious curative effect in the treatment of stable angina pectoris.
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