血清T3/T4值对Graves病甲亢与亚甲炎引起的甲状腺毒症的分析  

Serum T3 to T4 ratio in Graves' thyrotoxicosis and subacute thyroiditis

作　　者：苟静[1] 靳瑾[1] 阿布力克木.吐尔地 

机构地区：[1]新疆医科大学第五附属医院内分泌科 [2]新疆医科大学第一附属医院内分泌科,新疆乌鲁木齐830000

出　　处：《新疆医科大学学报》2010年第10期1229-1231,共3页Journal of Xinjiang Medical University

摘　　要：目的探讨血清T3/T4值在诊断Graves病甲亢和亚急性甲状腺炎引起的甲状腺毒症中的临床价值。方法回顾性分析2004年8月～2008年10月在新疆医科大学第一附属医院内分泌科就诊的Graves病甲状腺功能亢进症(124例)及亚急性甲状腺炎患者(35例)的病例资料,对已确诊的患者血清T3/T4的比值进行统计学分析。结果 Graves病甲亢组及亚甲炎组患者血清T3/T4值差异具有统计学意义(P<0.01),Graves病甲亢组T3/T4值高于亚甲炎组。Graves病甲亢组血清FT3/FT4值较高,而亚甲炎组较低,其差异具有统计学意义(P<0.01)。结论在临床工作中可以通过观察血清T3/T4、FT3/FT4值来简单判断甲状腺功能亢进症的不同病因,并给予积极对症治疗。Objective To search for simple and practical parameters（the triiodothyronine/thyroxine ratio）that might allow differentiation between the two entities.Methods Analyzed retrospectively the data of patients in endocrine department of the First Affiliated Hospital of Medical University of Xinjiang from August 2004 to October 2008.Results In comparison between groups,triiodothyronine（T3）/tetraiodothyronine（T4）ratio was higher in group of Graves＇ disease than in group of subacute thyroiditis.The differences between Graves＇ disease and subacute thyroiditis group were significant（P0.01）.Free triiodothyronine（FT3）/free thyroxine（FT4）ratio was higher in group of Graves＇ disease than in group of subacute thyroiditis.The differences between Graves＇ disease and subacute thyroditis group were significant（P0.01）.Conclusion Serums T3/T4 is as effective as radioactive iodine uptake for differentiation of destruction-induced thyrotoxicosis（subacute thyroiditis for painless）from Graves＇ thyrotoxicosis.We also can use it for difference of thyrotoxicosis from various causes.

关 键 词：T3/T4 FT3/FT4 GRAVES病 甲亢 亚急性甲状腺炎 

分 类 号：R581[医药卫生—内分泌]