食管癌血清吸收光谱的探讨  

Study on serum absorption spectrum of esophageal cancer

作　　者：张晓冬[1] 杨坤[1] 张爱贞[2] 

机构地区：[1]郑州轻工业学院技术物理系,河南郑州450002 [2]郑州大学第五附属医院,河南郑州450052

出　　处：《激光与红外》2010年第12期1355-1357,共3页Laser & Infrared

基　　金：河南省教育厅自然科学研究计划项目(No.2010A510019)资助

摘　　要：我国是世界上食管癌发病的高发地区。目前,食管癌患者常用的治疗方法为化疗,若能早期发现并及时治疗,则对于患者来说,意味着较高的生存机会。运用分光光度计对正常人与食管癌患者血清进行光谱检测,每例样品经标准化配置后,经检测得到紫外-可见吸收光谱的光谱数据,根据Origin软件进行统计分析处理并发现:食管癌患者血清在414 nm处所产生的吸光度数值明显比正常人血清要高,并且食管癌患者血清某些特征谱带的光谱比数值(I278/I253)与正常人血清的相比产生明显差异。因此,这些血清吸收光谱中某些特征谱带的光谱数据经过处理后,可以为医生早期快速诊断食管癌提供了新的思路。China is the high occurrence areas of esophageal cancer in the world.At present,the treatment for esophageal cancer patients is used to be the chemotherapy which makes patients to suffer a lot.If early detection and timely treatment is achieved,that means a higher chance of survival.In this paper spectrophotometer is used to check the serum spectra of esophageal cancer patients and healthy men.Samples are normally configured for each case at first and then tested with ultraviolet-visible absorption spectrum.Using Origin software for statistical analysis,it is found that：esophageal cancer patients′ serum have a much higher absorption value at 414 nm than the normal ones.And there exists obvious difference between the spectral ration characteristic of esophageal cancer patients and the normal people（I278/I253）.Therefore,these serum absorption spectra data can be used in rapid and early diagnosis of esophageal cancer.

关 键 词：光学 吸收光谱 吸光度比值 食管癌血清 

分 类 号：O433.5[机械工程—光学工程]