Lewis酸催化下苯乙酮型苯并吡喃的合成  

Synthesis of Acetophenone Benzopyran Derivative Catalyzed by Lewis Acids

作　　者：齐小燕[1] 伍林[1] 王建国[1,2] 易德莲[1] 周锦霞[1] 刘敏[1] 彭功名[1] 

机构地区：[1]武汉科技大学应用化学研究所,武汉430081 [2]九江学院化学化工学院,九江332005

出　　处：《有机化学》2010年第12期1944-1948,共5页Chinese Journal of Organic Chemistry

摘　　要：以2,4-二羟基苯乙酮(1a)为原料,通过O-异戊烯基化和Lewis酸催化分子内关环反应,合成了苯乙酮型苯并吡喃化合物3a.产物结构经UV,IR,1HNMR,13CNMR和元素分析表征,并对反应条件进行了初步探讨.A acetophenone benzopyran derivative was prepared from 1-（2,4-dihydroxyphenyl）ethanone （1a） through O-prenylation and Lewis acids catalyzed intramolecular cyclization reaction. The structure of product 3a was characterized by UV, IR, 1H NMR, 13C NMR spectra and elemental analysis, and the reac-tion conditions were discussed.

关 键 词：O-异戊烯基化 苯并吡喃 LEWIS酸 合成 

分 类 号：O626[理学—有机化学]