念慈庵川贝枇杷膏止咳化痰平喘药效学的研究  

Experimental Studies on Antitussive,Expectorant and Antiasthmatic Effects of Niancian Chuanbei Pipa Gao

作　　者：兰云 尹军强[2] 罗文敏 吴良才[2] 贾强[1,3] 

机构地区：[1]贵州省生物研究所,贵阳550009 [2]中山大学附属第一医院,广州510275 [3]贵州科学院贝科生物资源研究开发中心,贵阳550009

出　　处：《贵州科学》2010年第4期98-100,120,共4页Guizhou Science

基　　金：贵州省农业公关项目:黔科合农G字[2009]4013;贵州省自然基金:黔科合J字[2009]2290;贵州省委组织部高层次人才基金:TZJF-2009-45;贵州省农业重点公关项目:黔科合NY字[2009]3021;贵州科学院人才引进项目:黔科院人合字[2009]01

摘　　要：研究念慈庵川贝枇杷膏的止咳、化痰和平喘药效作用。方法:采用小鼠氨水引咳法观察止咳作用;用小鼠酚红排泌法观察化痰作用;用喷雾致喘法观察平喘作用。结果:念慈庵川贝枇杷膏能明显延长引起半数小鼠咳嗽的氨水喷雾时间(EDT50),能促进小鼠气管酚红的排泌,对组胺和氯化乙酰胆碱混合液引起的豚鼠哮喘具有抑制作用。结论:念慈庵川贝枇杷膏具有明显止咳、化痰和平喘作用。To observe the antitussive and expectorant effects of Niancian Chuanbei Pipa Gao. Methods the model of cough induced by ammonia liquor spray in mice was used to observe the antitussive effect; the model of phenel red execretion in mice was used to observe the expectorant effect. Results the Niancian Chuanbei Pipa Gao could inhibit the cough induced by ammonia in mice and increase phenol red output of trachea in mice. Conclusion The Niancian Chuanbei Pipa Gao have a significant a antitussive and expectorant effects.

关 键 词：念慈庵川贝枇杷膏 止咳 化痰 

分 类 号：R943[医药卫生—药剂学]