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作 者:贾睿[1] 施艳红[2] 何培民[1] 郭跃伟[2]
机构地区:[1]上海海洋大学水产与生命学院,上海201306 [2]中国科学院上海药物研究所,上海201203
出 处:《中国天然药物》2010年第6期422-424,共3页
基 金:supported by the National Science & Technology Major Project (No 2009ZX09301-001);Natural Science Foundation of China (Nos 21072204, 30730108 and 20721003);Science Foundation for the Excellent Youth Scholars of Shanghai (No ssc09001);STCSM International Cooperation Project between SIMM/China and ICB/Italy (No 10540702900);NSFC-TRF International Cooperation Project (No 20911140471);the CAS Key Project (grant KSCX2-YW-R-18)~~
摘 要:目的:研究扭曲肉芝软珊瑚的化学成分。方法:综合利用各种层析方法分离和纯化化合物, 并利用光谱学和理化性质来鉴定化合物结构。结果:从中分离得到5个化合物, 分别鉴定为 brassicolide (1), emblide (2),methyl tortuoate A (3), methyl tortuoate B (4), (24S)-24-methylcholestane-1,3, 5, 6, 25-pentol 25-monoacetate (5)。结论:化合物1,2和5都是首次从该珊瑚中分离得到。AIM: To study the chemical constituents of Sarcophyton tortuosum. METHODS: The chemical constituents were isolated and purified by various chromatographic techniques. Their structures were determined on the basis of physical properties and spectroscopic data. RESULTS: Five compounds were isolated and elucidated as brassicolide (1), emblide (2), methyl tortuoate A (3), methyl tortuoate B (4), and (24S)-24-methylcholestane-1, 3, 5, 6, 25-pentol 25-monoacetate (5). CONCLUSION: Compounds 1, 2 and 5 were isolated from this species for the first time.
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