黑边假龙胆的化学成分(英文)  

Chemical Constituents of Gentianella azurea

作　　者：史可丽[1] 王业清[1] 蒋茜[1] 廖志新[1] 

机构地区：[1]东南大学化学化工学院制药工程系,南京210009

出　　处：《中国天然药物》2010年第6期425-428,共4页

基　　金：supported by the National Natural Science Foundation of china(No30770233)

摘　　要：目的:对黑边假龙胆的化学成分进行研究。方法:应用硅胶柱色谱,Sephadex LH-20和Rp-18反相柱色谱的方法分离和纯化化合物, 通过光谱方法及理化性质鉴定化合物结构。结果:分离得到9个化合物,分别鉴定为1-羟基-3, 7, 8-三甲氧基酮(1)、1,8-二羟基-3, 5-二甲氧基酮(2)、木犀草素(3)、β-胡萝卜苷(4)、海波拉亭(5)、1-羟基-3,5, 8-三甲氧基酮(6)、熊果酸(7)、雏菊叶龙胆(8)、木犀草素-5-O-β-D-葡萄糖苷(9)。结论:化合物 1～3、5～7、9均首次从该种植物中分离得到。AIM： To investigate the chemical constituents of Gentianella azurea. METHODS： The chemical con-stituents were isolated and purified by silica gel, Sephadex LH-20 and Rp-18 column chromatographic methods. Their structures were elucidated on the basis of physical characteristics and spectroscopic data. RESULTS： Nine compounds were obtained and their structures were identified as 1-hydroxyl-3, 7, 8-trimethoxyxanthone （1）, 1, 8-dihydroxyl-3, 5-dimethoxyxanthone （2）, luteolin （3）, β-daucosterol （4）, hypolaetion （5）, 1-hydroxyl-3, 5, 8-trimethoxyxanthone （6）, ursolic acid （7）, swertianolin （8）, and luteolin-5-O-β-D-glucoside （9）. CONCLUSION： Compounds 1-3, 5-7, 9 are re-ported in this plant for the first time.

关 键 词：假龙胆属 黑边假龙胆 化学成分 

分 类 号：R284.1[医药卫生—中药学]