半导体激光联合药物治疗PHN疗效观察  

Effects of Semiconductor Laser Combined with Drugs on Postherpetic Neuralgia

作　　者：赵明[1] 漆军[2] 李恒进[2] 汪月强 

机构地区：[1]浙江省温州医学院皮肤科 [2]解放军总医院皮肤科 [3]解放军91765部队岸勤部卫生科

出　　处：《中华全科医学》2011年第1期28-28,134,共2页Chinese Journal of General Practice

摘　　要：目的探讨半导体激光联合药物治疗治疗带状疱疹后遗神经痛(posttherpetic neuralgia,PHN)的疗效。方法将80例带状疱疹后遗神经痛患者随机分为治疗组和对照组,治疗组40例采用半导体激光照射治疗,1次/d,每次10 min,共治疗10次,同时口服维生素B1片、甲钴胺片;对照组40例仅口服维生素B1片、甲钴胺片,用法与治疗组相同。10 d后比较两组患者治疗前后疼痛缓解情况,疼痛评价采用视觉模拟评分法(visual analogue scale,VAS)。结果两组治疗后VAS评分均较治疗前下降,治疗组下降程度大于对照组。治疗组治愈14例,显效18例,有效率为80%,治愈率为35%;对照组治愈5例,显效14例,有效率为47.5%,治愈率为12.5%,两组患者均未出现明显不良反应。治疗组有效率明显高于对照组(P<0.01),治愈率也高于对照组(P<0.05)。结论半导体激光联合药物治疗是一种安全有效的治疗带状疱疹后遗神经痛的方法。Objective To investigate the efficacy of semiconductor laser combined with drugs in treatment of postherpetic neuralgia（PHN）. Methods Eighty patients with PHN were randomly divided into two groups. Forty cases in treatment group were treated with semiconductor laser, once a day, ten minutes every time, total ten days, meanwhile, the patients were given vitamin B1 tablets and mecobalamin tablets; the patients in control group were treated only with vitamin B1 tablets and mecobalamin tablets. Tile pain was assessed with visual analogue scale （VAS） before and after the treatment. Results The scores of VAS were decreased in both groups after the treatment,and obviously in the treatment group. In treatment group, 14 cases were cured, and 18 cases achieved excellent therapeutic efficacy, the effective rate and the cure rate were 80% and 35%, respectively. In control group,5 cases were cured,14 cases achieved excellent,the effective rate and the cure rate were 47.5% and 12.5% ,respectively. The effective rate in treatment group was significantly superior to that in control group（P 〈0.01 ） and the cure rate in treatment group was also superior to that in control group（ P 〈 0.05 ）. Conclusion Semiconductor laser combined with drugs is safe and effective for PHN

关 键 词：半导体激光 带状疱疹 神经痛 

分 类 号：R752.12[医药卫生—皮肤病学与性病学] R454.21[医药卫生—临床医学]