血培养联合血清降钙素原检测对菌血症的诊断价值  

Clinical significance of procalcitonin detection combined with blood culture in diagnosis of bacteremia

作　　者：马莉[1] 孙光伟[1] 许珣[1] 

机构地区：[1]解放军第一七四医院检验科,福建厦门361003

出　　处：《检验医学与临床》2011年第1期25-26,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨血培养联合血清降钙素原(PCT)检测对菌血症的诊断价值。方法对264例肺炎发热患者血标本用酶联荧光分析法(ELFA)测定血清PCT,同时进行血培养;对PCT阳性而血培养阴性患者的血标本进行第2次血培养。结果 PCT阳性96例,占36.4%,血培养阳性33例,占12.5%;63例结果不一致患者标本第2次血培养检出阳性15例,血培养阳性共48例,占18.2%。结论血培养联合血清PCT检测对菌血症的诊断有指导意义。Objective To evaluate the diagnostic value of procalcitonin（PCT） detection combined with the blood culture to bacteremia. Methods The method of enzyme-linked immunofluorescent assay（ELFA） was used to detect the serum levels of PCT in 64 patients with fever and 21 healthy people as control. At the same time, the sam ples were performed the blood culture. The patients with positive PCT and negative blood culture received the blood culture again. Results The serum PCT was positive in 96 cases,accounting for 36.4%. The blood culture was positive in 33 cases, accounting for 12.5 %. 63 cases of inconsistent results, 15 cases were positive in the second blood culture. The blood culture had the positive results in 48 cases all together,accounting for 18.2 %. The serum PCT levels in pneumonia patients was more obvious changes than the normal group（P〈0.01）. The serum PCT levels in pneumonia patients was more obvious changes than the blood culture positive resuhs（P〈0.05）Conclusion PCT detec tion and the blood culture may be used as guideline of diagnosing bacteremia.

关 键 词：菌血症/诊断 降钙素 血培养 肺炎 发热 

分 类 号：R51[医药卫生—内科学]