舒芬太尼复合药物用于双下肢烧伤患者自控镇痛的临床比较  

The Clinical Observation Of Sufentanil Composite Drug In The Automatic Control Analgesia Of Burn Patients

作　　者：杜剑鸿[1] 卓阳[1] 陈丽芬[1] 李晟[1] 

机构地区：[1]中国人民解放军第一一八医院,浙江温州325000

出　　处：《医学信息（中旬刊）》2011年第1期5-7,共3页Medical Information Operations Sciences Fascicule

摘　　要：目的:观察和比较舒芬太尼加凯纷静脉自控镇痛及舒芬太尼合并罗哌卡因硬膜外自控镇痛用于双下肢烧伤患者行植皮去痂术术后镇痛效果及副作用。方法:将中度双下肢烧伤男性患者90例随机分为两组,每组各45例。PCIA组使用舒芬太尼复合凯纷静脉自控镇痛,PCEA组使用舒芬太尼复合罗哌卡因硬膜外自控镇痛。镇痛开始后h2、h4、h12、h24和h48时点进行多参数评估,镇痛效果评估指标采用视觉模拟评分法(VAS),观察和记录各时段的血压、脉搏、呼吸和血氧饱和度值,记录出现的副作用。结果:两组镇痛效果无显著性差异(p>0.05),两组不良反应无显著性差异(p>0.05),术后Ramsay镇静评分,有效按压镇痛泵次数及48h舒芬太尼用量两组间无显著性差异(p>0.05)。结论:两组患者的术后镇痛效果及不良反应发生率相当,但舒芬太尼复合凯纷行PCIA使用方便,无双下肢运动神经阻滞且导管不易脱出,更值得临床推广。Objective ： To observe the difference of effect and side effect between sufentanil composite flurbiprofen axetil in the vein automatic control analgesia and sufentanil composite ropivacaine in the controlled epidural analgesia of burn patients. Methods：Divide 90 cases into 2 groups ,45 cases in each group. PCIA group should be used for sufentanil composite flurbiprofen axetil in the vein automatic control analgesia;PCEA group should be used for sufentanil composite ropivacaine in the controlled epidural analgesia When analgesic effect started at h2 ,h4,h12,h24 and h48, muhiparameter were evaluated according to visual analog score （YAS）. Observed and recorded the values of the blood pressure, pulse, respiration and pulse oximeter saturation value, side effects. Results：Analgesic effect and side effect between PCIA group and PCEA group was no significant difference （ p 〉 0.05 ） ; and the different periods of Ramsay score and the dose of sufentanil between PCIA and PCEA group was no significant difference （ p 〉 0. 05 ）. Conclusion： Sufentanil composite flurbiprofen axetil on moderate and severe pain in the early stages of burn patients have a betteranalgesic effect, and relatively safe,less side effects, and is worthy to recommend.

关 键 词：舒芬太尼 氟比洛芬 罗哌卡因 烧伤 自控镇痛 

分 类 号：R614.42[医药卫生—麻醉学]