572名儿童乙肝表面抗体定量检测结果分析  

Analysis of Quantitative Testing for Anti-HBs in 572 Children Cases

作　　者：陈丽彬[1] 卢亚陵[1] 钟薇[1] 

机构地区：[1]成都儿童专科医院,四川成都610041

出　　处：《医学信息（中旬刊）》2011年第1期35-36,共2页Medical Information Operations Sciences Fascicule

摘　　要：目的:了解乙肝表面抗体含量与1至6岁儿童各年龄段间的变量关系。方法:运用双抗原夹心时间分辨免疫荧光分析法(IFMA法)测定样本抗-HBs浓度值,应用统计软件SAS进行数据分析。结果:随年龄增长,儿童抗-HBs含量和抗-HBs阳性率也随之下降(P<0.01)。结论:乙肝疫苗免疫效果随免疫年限的增长而渐弱,接种乙肝疫苗后应检验接种效果,以便及时加强免疫。Objective ： To learn the relationship between HBsAb level and range of the ages of children （ 1 - 6 ）. Methods ： Venous blood samples of 572 children were taken and made quantitative testing for anti - HBs level by means of IFMA. Microsoft SAS was used to statist the results. Results ： The positive rate of HBsAb and the HBsAb level decreased with ages increase （ P 〈 0. 01 ）. Conclusion ： Immunologic effects of Hepatitis B vaccine were decreased with the expansion of time span. After receiving of Hepatitis B vaccine,it is advisable to examine the result of the vaccination so that the boost vaccine can be. taken on time.

关 键 词：儿童 乙肝疫苗 乙肝表面抗体 定量检测 

分 类 号：R512.62[医药卫生—内科学]