Cardiac magnetic source imaging based on current multipole model  

作　　者：唐发宽 王倩 华宁 陆宏 唐雪正 马平 

机构地区：[1]Department of Cardiology,The 309th Hospital of PLA [2]Department of Physics,State Key Laboratory for Artificial Microstructure and Mesoscopic Physics,Peking University

出　　处：《Chinese Physics B》2011年第1期258-266,共9页中国物理B（英文版）

基　　金：Project supported by the State Key Development Program for Basic Research of China(Grant No.2006CB601007);the National Natural Science Foundation of China(Grant No.10674006);the National High Technology Research and Development Program of China(Grant No.2007AA03Z238)

摘　　要：It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current multipole model expanded to the first order terms. This magnetic imaging is realized in a reconstruction plane in the centre of human heart, where the current dipole array is employed to represent realistic cardiac current distribution. The current multipole as testing source generates magnetic fields in the measuring plane, serving as inputs of cardiac magnetic inverse problem. In the heart-torso model constructed by boundary element method, the current multipole magnetic field distribution is compared with that in the homogeneous infinite space, and also with the single current dipole magnetic field distribution. Then the minimum-norm least-squares （MNLS） method, the optimal weighted pseudoinverse method （OWPIM）, and the optimal constrained linear inverse method （OCLIM） are selected as the algorithms for inverse computation based on current multipole model innovatively, and the imaging effects of these three inverse methods are compared. Besides, two reconstructing parameters, residual and mean residual, are also discussed, and their trends under MNLS, OWPIM and OCLIM each as a function of SNR are obtained and compared.It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current multipole model expanded to the first order terms. This magnetic imaging is realized in a reconstruction plane in the centre of human heart, where the current dipole array is employed to represent realistic cardiac current distribution. The current multipole as testing source generates magnetic fields in the measuring plane, serving as inputs of cardiac magnetic inverse problem. In the heart-torso model constructed by boundary element method, the current multipole magnetic field distribution is compared with that in the homogeneous infinite space, and also with the single current dipole magnetic field distribution. Then the minimum-norm least-squares （MNLS） method, the optimal weighted pseudoinverse method （OWPIM）, and the optimal constrained linear inverse method （OCLIM） are selected as the algorithms for inverse computation based on current multipole model innovatively, and the imaging effects of these three inverse methods are compared. Besides, two reconstructing parameters, residual and mean residual, are also discussed, and their trends under MNLS, OWPIM and OCLIM each as a function of SNR are obtained and compared.

关 键 词：cardiac magnetic imaging current multipole heart-torso model inverse method 

分 类 号：O482.5[理学—固体物理]