基于孕激素受体基因的类人猿亚目的分子系统学研究  

Phylogenetic Analysis of Anthropoidea Based on Progesterone Receptor Gene Sequences

作　　者：陈曹逸[1] Derek Wildman 朱新宇[1] 刘伟 王康乐[1] 苏敏[7] 谭湘陵[1] 

机构地区：[1]南通大学生命科学院,江苏南通226007 [2]Perinatology Research Branch,National Institute of Child Health and Human Development/National Institutes of Health,Department of Health and HumanServices,Bethesda,mdusa20892 [3]Center for Molecular Medicine and Genetics,Wayne State University [4]Departments of Obstetrics and Gynecology,Wayne State University [5]复旦大学上海医学院医学分子病毒学重点实验室,上海200032 [6]复旦大学生物医学研究院,上海200032 [7]南通大学附属医院妇产科,江苏南通226001

出　　处：《四川动物》2011年第1期11-15,共5页Sichuan Journal of Zoology

摘　　要：通过对类人猿亚目中部分种类的孕激素受体基因进行分析,重建类人猿亚目的系统发育关系。扩增并测定了来源于14个属的类人猿亚目物种的孕激素受体编码区序列,并基于这一序列数据,分别采用邻接法、最大简约法和最大似然法重建了系统发育关系。除了阔鼻下目,3种方法构建的系统发生树的拓扑结构类似且各节点支持率高。重建的人猿超科和猴超科内部亲缘关系支持多数人所认可的分类系统。本研究为黑猩猩和人的姐妹群关系提供了证据,提示黑猩猩比大猩猩或其他猿猴更接近人类。阔鼻下目中蜘蛛猴科、卷尾猴科和僧面猴科三者之间的系统发育关系在本研究中未得到很好辨析。The aim of this study was to reconstruct the phylogenetic relationships of Anthropoidea. The coding region of the progesterone receptor gene of fourteen species belonging to fourteen genera of Anthropoidea were amplified and sequenced. Phylogeuetic trees based on the progesterone receptor genes＇ coding region sequences were reconstructed using neighbor joining （NJ） , maximum parsimony （MP） and maximum likelihood （ML） methods. All phylogenetic reconstructions yielded trees with very similar topologies with high bootstrap values except the topologies of families in Platyrrhini. The results indicated that there were two principle clades in Anthropoidea： the Catarrhini and Platyrrhini. Catarrhiui consisted of Hominoidea and Cercopithecidae. The phylogenies within Cercopithecidae and Hominoidea were recovered with very high bootstrap values, which agree with the widely accepted taxonomic view of Cercopithecidae and Hominoidea. The results also suggested that humans were most closely related to chimpanzees and present evidence for a sister relationship between humans and chimpanzees. Platyrrhini consisted of three principle families： Atelidae,Cebidae and Pitheciidae. However, the phylogenetic relationships among Atelidae, Cebidae and Pitheciidae were not well resolved in our analyses.

关 键 词：孕激素受体基因 系统发育关系 类人猿亚目 

分 类 号：Q951.3[生物学—动物学]