鸭源副黏病毒的致病性试验  

Pathogenicity of duck paramyxovirus

作　　者：吴焕荣[1] 刁有祥[1] 李宏梅[1] 孙洪磊[1] 颜赟[1] 孙杰[1] 李瑶瑶[1] 

机构地区：[1]山东农业大学动物科技学院,山东泰安271018

出　　处：《中国兽医学报》2011年第1期36-39,共4页Chinese Journal of Veterinary Science

基　　金：山东省科技攻关资助项目(2007GG30009001)

摘　　要：利用鸭源副黏病毒(DPMV)SDFC株分别人工感染21日龄健康非免疫樱桃谷肉鸭和SPF雏鸡,观察试验鸡、鸭的发病情况及临床症状,于感染后不同时间剖杀,观察各组织器官的病理变化,并进行病理组织学研究。结果显示,鸭感染DPMV后发病率为100%,死亡率为43.3%;而鸡感染后的发病率、死亡率均为100%。病理组织学研究结果显示,鸭感染DPMV后,以心脏、肺脏、肝脏、肾脏、脾脏、法氏囊广泛性出血、变性为特征,消化道病变较轻微;而鸡感染DPMV后,各组织器官广泛性出血,脾脏、胸腺、法氏囊、肝脏、胰腺、肾脏、心肌组织细胞出现不同程度的变性、坏死;食管、腺胃和各段肠管广泛性出血,并伴有黏膜脱落。结果表明,DPMV对鸡、鸭均有较强的致病性,而与鸡相比,对鸭的致病性较弱。To study the incidence,clinical symptom and compare the pathohistological changes in ducks and chickens which were sampled at different time,30 healthy non-immune cherry valley ducks and 30 SPF chickens were challenged with duck paramyxovirus at 21-day-old.The results showed that the morbidity and mortality were 100% and 43.3% respectively in ducks and 100% in chickens.Histopathological results showed that in ducks group,the heart,lung,liver,kidney,spleen,bursa completely suffered with hemorrhage and degeneration,but the pathological changes in digestive tract were observed slightly;in chickens group,the extensive hemorrhage were found in tissues.The degeneration and necrosis in different degree were observed in spleen,thymus,bursa,liver,pancreas,kidney and cordiac muscle tissues.The extensive hemorrhage were discovered in oesophagus,stomachus glandularis and all intestinal canals,which accompanied with mucosa desquamation.The results showed that the DPMV caused high pathogenicity to ducks and chickens.Compared with chickens,the pathogenicity of DPMV to ducks was slighter.

关 键 词：鸭源副黏病毒 鸡 鸭 致病性 

分 类 号：S852.65[农业科学—基础兽医学]