儿童门脉高压症病因和预后回顾分析  

Retrospective studies of etiology and prognosis in inpatient children with portal hypertension

作　　者：罗学群[1] 周李[1] 黄耘[1] 

机构地区：[1]中山医科大学附属第一医院儿科

出　　处：《中国实用儿科杂志》1999年第7期423-424,共2页Chinese Journal of Practical Pediatrics

摘　　要：目的了解住院儿童门脉高压症的病因和预后。方法回顾性分析１９７８～１９９７年共２０年的住院病例５３例，随访４０例，随访时间为０５～１２年，中位数１３年。结果９０年代以后儿童门脉高压症的住院率有上升的趋势，诊断的病因亦增多；病因主要是门脉海绵样变、门脉性肝硬化和先天性胆道闭锁，遗传代谢病亦占有一定的比例；在主要病因中，以先天性胆道闭锁所致的门脉高压症预后最差，门脉性肝硬化的预后极不一致，部分预后良好，门脉海绵样变以分流术后的预后较好。结论儿童门脉高压症的病因构成与成人相比有明显不同的特点，其预后与病因和治疗方式有关，临床上应有所认识。Objective To investigate the etiology and prognosis of inpatient children with portal hypertension.Methods 53 cases under the age of 14 of our hospital during 1978～1997 were analysed.40 cases had been followed up for 0 5～12 years(median 1 3 year).Results The constituent ratio of the inpatient children with portal hypertension and the kinds of etiologies diagnosed had risen since 1990's.The main etiologies in this group were portal cavernoma,portal cirrhosis and congenital bilary atresia.Some are genetic and metabolic disease.Among these main etiologies,the prognosis of bilary atresia was the worst.The one of portal cirrhosis was not uniform,some had good outcome.Portal cavernoma had better outlook when the surgery treatment was portosystemic shunt.Conclusion The constituent ratio of the etiology of portal hypertension in children is quite different from that in adult.The prognosis is related to the etiology and the way of treatment.

关 键 词：儿童 门脉高压症 病因 预后 

分 类 号：R726.573.4[医药卫生—儿科]