妊高征1号治疗妊娠期高血压疾病疗效观察  

Therapeutic effect of rengaozhengl in treatment of gestational hypertension

作　　者：祝参[1] 李小姝[1] 连晓红[1] 李宏英[1] 

机构地区：[1]郑州大学第二附属医院妇产科,450014

出　　处：《中国实用医刊》2011年第1期7-9,共3页Chinese Journal of Practical Medicine

基　　金：基金项目：河南省卫生厅基金资助项目（102300410071）

摘　　要：目的探讨以杜仲颗粒为主的中药加减的妊高征1号治疗妊娠期高血压疾病的临床治疗效果。方法将62例妊娠期高血压疾病患者随机分为两组，妊高征1号组（A组）32例，常规治疗组（B组）30例，观察保守治疗后两组尿蛋白含量、血清中尿酸含量、保守治疗时间及新生儿结局等情况。结果①A组从尿蛋白（一）发展到尿蛋白（＋＋＋）平均需要（14．3±3．5）d，而B组需要（6．5±1．8）d。终止妊娠时A组尿蛋白以轻中度为主，孕周已达到（35．6±3．4）周，继续妊娠会增加孕妇肾脏功能损害；B组以重度为主，孕周为（33．7±2．8）周，二者比较差异有统计学意义（P〈0．05）；②A组保守治疗的时间平均为（26±4）d，B组保守治疗平均时间（14±3）d，二者比较差异有统计学意义（P〈0．05）；③A组与B组相比，新生儿的存活率增加。结论妊高征1号能延缓妊娠期高血压疾病患者尿蛋白加重的病程，减轻肾脏功能损害，延长孕周，提高新生儿的存活率。Objective To explore the therapeutic effect of rengaozhengl with eucommia ul-moides oliver granule in treatment of gestational hypertension. Methods Sixty - two cases hypertension were randomly divided into two groups, 32 cases in group A （ rengaozhengl ） goup B （conventional therapy）. To observe urine protein level, uric acid in blood serum, treatment time and neonate outcomes in expectant treatment. Results （1）The urine protein 1 of gestational ,30 cases in conservative evel in group A from negative to （ ＋ ＋ ＋ ） need （14.3 ±3.5）days, group B need （6.5±1.8）days. The urine pro- tein level in group A was light and midrange of termination of pregnancy, but had （35.6±3.4） gestational weeks, continue pregnancy can raise kidney functional lesion. Group B with （33.7 ±2.8 ） gestational weeks was high level. There were significantly statistical differences between group A and group B （ P 〈 0.05 ） ; （2）Conservative treatment average time was （ 26±4 ） days in group A and （ 14 ± 3 ） days in group B, there was significantly statistical difference （ P 〈 0.05 ） ; （3）Neonate survival rate was increased in group A, compared with group B. Conclusions Rengaozhengl can delay kidney functional injury,prolong gestational weeks, elevate neonatal survival rate.

关 键 词：妊娠期高血压疾病 妊高征1号 

分 类 号：R714.246[医药卫生—妇产科学]