艾滋病合并巨细胞病毒性视网膜炎19例  

The clinical characteristics of cytomegaloviral retinitis in 19 cases with AIDS

作　　者：孙挥宇[1] 毛菲菲[1] 李丹[1] 何宏宇[1] 许雪静[1] 柳月红[1] 陈帆[1] 

机构地区：[1]首都医科大学北京地坛医院眼科,100015

出　　处：《眼科》2010年第6期376-379,共4页Ophthalmology in China

基　　金：首都医学发展科研基金(2009-3155)

摘　　要：目的 了解艾滋病合并巨细胞病毒性视网膜炎的临床特征.设计回顾性病例系列.研究对象北京地坛医院眼科诊治的艾滋病合并新发巨细胞病毒性视网膜炎患者19例29眼.方法 对所有19例患者29眼进行了与艾滋病相关的免疫学检测及肝肾功能检查 所有患者进行视力、眼压、裂隙灯、视野以及眼底照相等眼科检查,并观察其临床特征.主要指标视力,CD4＋细胞,眼底改变.结果 19例患者中,10例双眼发病.中心型巨细胞病毒性视网膜炎5例6眼,其视力指数～0.4 周边型9例15眼,其中14眼视力〉0.5 混合型5例8眼,其中7眼视力〈0.6.17例CD4＋细胞≤50个/μl.15例合并其他部位感染.结论 巨细胞病毒性视网膜炎是艾滋病常见眼部并发症,周边型是其常见类型.CD4＋细胞≤50个/μl的患者更易患病,其视力预后差.Objective To investigate characteristics of cytomegalovirus retinitis in AIDS patients. Design The retrospective case series. Particpants 19 AIDS patients （29 eyes） with active cytomegalovirus retinitis. Methods All 19 patients were evaluated with general and ophthalmic examination and the clinical characteristics were analyzed. Main Outcome Measures Visual acuity, CD4＋ cell counts, ocular fundus changes. Results In all 19 patients with cytomegalovirus retinitis, 10 patients were bilateral. The posterior type of the retinitis was observed in 5 patients （6 eyes）, whose visions were 0.4 or less; The periphery type was observed in 9 patients （15 eyes）, in which the visions of 14 eyes were 0.5 or better; Mixed type was observed in 5 patients （8 eyes）, in which visions of 7 eyes were 0.6 or better. CD4＋ cell counts of 17 cases were no more than 50 per μl. 15 of 19 patients had complicated with other infections. Conclusion Cytomegalovirus retinitis is a common complication of AIDS. The periphery type is common. The patients whose CD4＋ cell were no more than 50 per μl were easy to be infected. The prognosis of cytomcgalovirus retinitis is poor.

关 键 词：艾滋病 巨细胞病毒性视网膜炎 

分 类 号：R512.91[医药卫生—内科学] R774.1[医药卫生—临床医学]