中国基因组学研究进展与发展态势  

The Recent Progress of Genomics Research in China

作　　者：冷方伟[1] 

机构地区：[1]中国科学院生物物理研究所,北京100101

出　　处：《生物化学与生物物理进展》2010年第12期1261-1264,共4页Progress In Biochemistry and Biophysics

摘　　要：20世纪90年代初,以完成人类基因组全序列测定和注释为核心任务的人类基因组计划在美国的领导下兴起.自1999年中国加入人类基因组计划到现在的10年时间里,中国基因组学得到了快速的发展,建立了先进的基因组学技术平台,并出色完成了多项重大基因组科学研究项目,对我国生命科学各个领域的发展产生了重要影响.结合我国基因组学研究现状,《中国科学C辑.生命科学》(Sci China Ser C-Life Sci)2009年第1期发表了中国基因组学专题,综述了基因组测序、分型,功能基因检测技术和生物信息学分析技术,以及肝癌、免疫和环境与工业微生物的基因组学研究等方面的研究工作.In the early 1990s,focusing on the total sequencing and annotation of the complete human genome as its core mission,the Human Genome Project（HGP） was initiated under the leadership of the USA.Since China joined the HGP in 1999,the genomics in China developed rapidly in the past ten years,establishing several genome centers with advanced technology platform,and organizing many grand scientific projects.The development of genomics lead to an unprecedented development in life science research and biotechnology development in China.To display the progress of genomics research in China,the first issue of Sci China Ser C-Life Sci（2009） organized a series of reviews focusing on this special topic.Some reviews analyze the future trend of genomics research and its scientific impact based on the technical perspectives of genomic sequencing,genotyping and functional genomics,while the others present the significant change of research strategy and technology brought in by the HGP with respect to liver cancer,immunology,and medical,environmental and industrial microbiology.

关 键 词：人类基因组计划 基因组学 基因组测序 基因分型 肝癌 免疫 病原菌 

分 类 号：Q751[生物学—分子生物学]