儿童变应性鼻炎患者症状及生活质量评估  

Analysis of symptoms and quality of life in Children with allergic rhinitis

作　　者：曹瑞娟[1] 许昱[1] 陶泽璋[1] 张怡[1] 陈婉仪[1] 邓爱玲[1] 

机构地区：[1]武汉大学人民医院耳鼻咽喉头颈外科,武汉430060

出　　处：《临床耳鼻咽喉头颈外科杂志》2010年第23期1071-1073,1076,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金："十一五"国家科技支撑计划资助项目(No:2007BAI18B15)

摘　　要：目的:评估儿童变应性鼻炎(AR)患者的症状和生活质量,研究儿童AR患者症状的严重程度与生活质量的相关性,同时研究皮肤点刺试验结果与患儿症状、生活质量的相关性。方法:用症状视觉模拟评分量表(VAS)评价患儿症状的严重程度,用儿童鼻结膜炎相关生活质量问卷(RQLQ)评价患儿的生活质量,记录皮肤点刺试验结果,并进行相关的统计学分析。结果:①RQLQ量表5个方面间及23个项目间比较差异有统计学意义(F=32.03,P<0.01;F=7.35,P<0.01),鼻部症状方面是儿童患者生活质量最受影响的方面,其中鼻塞、喷嚏、鼻痒是评分最高的项目,三者间差异无统计学意义。②两量表有显著相关,其中难以入睡、因症状而觉得尴尬评分与鼻涕在VAS评分呈正相关(r=0.230,P<0.05;r=0.325,P<0.01),夜间醒来次数评分与鼻痒、喷嚏的VAS评分呈正相关(r=0.385,P<0.01;r=0.231,P<0.05),注意力难以集中评分与难以入睡、夜间醒来次数评分呈正相关(r=0.316,P<0.01;r=0.525,P<0.01),易怒评分与难以入睡评分呈正相关(r=0.243,P<0.05)。③皮肤点刺试验结果与两量表的各方面及总分均无显著相关。结论:AR患儿鼻部症状的严重程度与其生活质量显著相关,鼻涕、鼻痒、喷嚏可能是影响睡眠质量的主要原因,而睡眠质量可能影响非鼻眼部症状和情感反应,鼻涕可能是导致患儿因症状而觉得尴尬的主要原因;变应原级别与症状的严重程度及生活质量无显著相关。Objective：To evaluate symptoms and quality of life in children with allergic rhinitis,and to evaluate the correlations among the skin prick tests results,symptoms and quality of life.Method：Visual analog scale （VAS）was used to assess the symptoms severity,rhinoconjunctivitis quality of life questionnaire（RQLQ）was used to assess quality of life,the skin prick tests results were recorded,and statistics analysis was carried out among them.Result：①There were significant differences among the five aspects of RQLQ（F=32.03,P0.01）,nasal symptoms aspect was the most affected aspect of quality of life,moreover,there were significant differences among all the items of RQLQ（F=7.35,P0.01）,the scores of nasal blockage,sneezing and rhinorrhea were the highest,there were no significant differences among them.②VAS was significantly correlated with RQLQ,moreover,the scores of unable to get to sleep and embarrassed by symptoms were significantly correlated with rhinorrhea VAS scores（r=0.230,P0.05;r=0.325,P0.01）,the score of wake up during the night was significantly correlated with nasal itching and sneezing VAS scores（r=0.385,P0.01;r=0.231,P0.05）,the score of can ＇t concentrate was significantly correlated with the scores of unable to get to sleep and wake up during the night（r =0.316,P0.01;r=0.525,P0.01）,the score of irritable was significantly correlated with the scores of unable to get to sleep（r=0.243,P0.05）.③The results of the skin prick tests were irrelated with VAS and RQLQ. Conclusion：Nasal symptoms severity may significantly correlated with the quality of life.Rhinorrhea,nasal itching and sneezing may be the main factors affecting the quality of sleep,while the quality of sleep may affect non-hay-fever symptoms and emotions,rhinorrhea may be the main factor affecting embarrassed by symptoms.The allergen level was irrelated with the symptoms severity and quality of life.

关 键 词：鼻炎 变应性 常年性 生活质量 量表 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]