蒙医灸疗法抗衰老组穴配伍规律实验研究  

Empirical Study on the Compatibility Laws of Acupoints for Anti-aging in Mongilian Medicine Moxibustion Therapy

作　　者：斯钦图 于天源[2] 阿古拉[1] 乌仁图雅[1] 斯琴[1] 布图雅[1] 陈英松[1] 乌云格日乐[1] 包伍叶[3] 那仁格日乐[3] 

机构地区：[1]内蒙古医学院,内蒙古呼和浩特010020 [2]北京中医药大学,北京100029 [3]内蒙古民族大学,内蒙古通辽028000

出　　处：《内蒙古民族大学学报（自然科学版）》2010年第6期675-680,共6页Journal of Inner Mongolia Minzu University：Natural Sciences

基　　金：国家自然基金地区科学基金项目(30760323)

摘　　要：目的:在前期研究基础上,通过实验研究探讨蒙医灸疗法抗衰老组穴配伍方法规律.方法:将160只Wistar大鼠随机分单穴组、双穴组和三穴组,采用D-半乳糖造模方法,观察和检测体重变化、SOD、CAT、MDA变化、脾脏(胸腺)指数以及学习能力、记忆力等指标.结果:从血清SOD、CAT、MDA变化、脾脏(胸腺)指数以及学习能力、记忆力等相关指标证明了顶会穴、火衰穴、胃穴、肾穴等四个穴位的抗衰老作用,二穴组配伍中的顶会穴、火衰穴配伍组和三穴组配伍中的顶会穴、火衰穴、肾穴配伍组与模型组比较,SOD活性、MDA、CAT含量均无显著差异(P>0.05),其他配伍组SOD活性均明显提高(P<0.01).从大鼠脾脏、胸腺指数变化上看,虽然各配伍组大鼠脾脏、胸腺指数比较模型对照组明显提高(P<0.01或P<0.05),但与正常对照组比较无明显差异(P>0.05).顶会穴与火衰穴配伍组、肾穴与火衰穴配伍组以及顶会穴、火衰穴、肾穴配伍组学习能力、记忆力与模型对照组比较无明显差异(P>0.05).结论:(1)D-半乳糖衰老模型适用于蒙医灸疗法抗衰老有效穴位的筛选和配伍规律实验研究领域(.2)具有抗衰老作用的顶会穴、胃穴、火衰穴、肾穴在不同配伍组穴情况下显示出配伍禁忌(.3)该研究为灸疗法抗衰老临床提供了客观依据,也为蒙医灸疗法作用机理研究提供了经验.Objective：On the basis of early research,taking Dinghui acupoint,Stomach acupoint,Huoshuai acupoint,Kidney acupoint these four acupoints as the breakthrough point,to investigate the compatibility laws of acupoints for anti-aging in Mongolian moxibustion therapy through experiment.Methods： 160 rats were randomly devided into single acupoint group,two acupoints group and three acupoints group.Using D-half lactose to make aging model,observed and examined the changes of weight,SOD,CAT,MDA,and the index of spleen（chest gland）,learning and memory function.Results： The change of serum SOD,CAT,MDA,and the index of pleen（chest gland）,learning and memory function showed that these four acupoints had anti-aging action.Compared with the model group,the SOD activity,MDA and CAT contents in two acupoints group of Dinghui acupoint combined with Huoshuai acupoint,three acupoints group of Dinghui acupoint combined with Huoshuai acupoint and Kidney acupoint,there were no remarkable differences（P0.05）,but SOD activity increased in other compatibility groups clearly（P0.01）.For the changing of spleen and chest gland in rats,though they increased in every compatibility group compared with the model group（P0.01 or P0.05）,there were no remarkable differences（P0.05） when compared with the normal group.Conclusion： 1）.D-half lactose aging models is suitable for the studying field of screening out the effective acupoints in Mongolian moxibustion therapy for anti-aging and their compatibility laws.2）.Dinghui acupoint,Stamoch acupoint,Huoshuai acupoint,Kidney acupoint have anti-aging action,but there are incompatibility in different compatibilities.3）.The experiment provides an objective basis for clinical Mongolian moxibustion treatment of resisting senility,and also provides a rich experience for Mongolian moxibustion therapy.

关 键 词：蒙医灸疗法 抗衰老 组穴配伍 实验研究 

分 类 号：R291.2[医药卫生—民族医学]