上海嘉定地区466例过敏性疾病患儿的变应原研究  

Clinical value of allergens in children with allergic diseases in Jiading district of Shanghai

作　　者：王莉莉[1] 李正秀[1] 曹兰芳[2] 

机构地区：[1]上海交通大学医学院附属仁济医院嘉定分院儿科 [2]上海交通大学医学院附属仁济医院儿科,上海201800

出　　处：《实用临床医药杂志（护理版）》2010年第12期16-19,共4页Journal of Clinical Medicine in Practice

基　　金：上海市科委重大课题资助项目(08411953100)

摘　　要：目的探讨上海嘉定地区过敏性疾病患儿的变应原特点及临床意义。方法用13种标准化的变应原点刺液,对上海嘉定地区466例过敏性疾病患儿进行皮肤点刺试验,并与上海市黄浦区454例过敏性疾病患儿及100例嘉定地区健康儿童检测结果进行比较。结果上海嘉定地区过敏性疾病患儿的皮肤点刺试验阳性率大小依次为:屋尘螨(59.38%)>粉尘螨(58.18%)>猫上皮(26.41%)>狗上皮(25.74%)>树Ⅰ(21.45%)>树Ⅱ(19.30%)>霉菌Ⅰ(17.69%)>霉菌Ⅱ(16.49%)>虾(16.00)>鸡蛋(15.55%)>牛奶(14.61%)>杂草(4.96%)>橡胶(3.89%)。上海市黄浦区过敏性疾病患儿的皮肤点刺试验阳性率大小依次为:屋尘螨(69.82%)>粉尘螨(40.31%)>虾(13.66%)>猫上皮(13.00%)>狗上皮=树Ⅰ(11.89%)>树Ⅱ(10.35%)>霉菌II(9.91%)>霉菌Ⅰ(7.49%)>牛奶(6.83)>橡胶(3.30%)>鸡蛋(3.08%)>杂草(0.88%)。差异均有统计学意义(P<0.05)。结论上海嘉定地区过敏性疾病患儿变应原的阳性率及种类与市区不同,并与年龄相关;但主要变应原和市区相同,仍以粉尘螨和屋尘螨为主。Objective To evaluate the feature and clinical value of allergens in children with allergic diseases in Jiading area of Shanghai.Methods Skin prick test（SPT） of 13 common allergens with standard prick liquid was performed in 466 children with allergic diseases in Jiading area of Shanghai,compared with 454 children with allergic diseases in Huangpu area of Shanghai and 100 healthy children in rural area of Shanghai.Results The positive rates of SPT for 13 types of allergens in children with allergic diseases in Jiading district are： dermatophagoides pteronyssinus（59.38%）,dermatophagoides farina（58.18%）,cat（26.41%）,dog（25.74%）,tree I（21.45%）, tree Ⅱ（19.30%）,aspergillus species Ⅰ（17.69%）,aspergillus species Ⅱ（16.49%）,shrimp（16.00%）,egg（15.55%）,milk（14.61%）,weed（4.96%） and rubber（3.89%）.Huangpu ared of Shanghai are： dermatophagoides pteronyssinus（69.82%）,dermatophagoides farina（40.31%）,shrimp（13.66%）,cat（13.00%）,dog（11.89%）,tree I （11.89%）,tree Ⅱ（10.35%）,aspergillus species Ⅱ（9.91%）,aspergillus species Ⅰ（7.49%）,milk（6.83%）,rubber（3.30%）,egg（3.08%） and weed（0.88%）.The difference was statistically significant（P0.05）.Conclusion The positive rates and types of allergens in children with allergic diseases in Jiading area are different from Huangpu area,and they are related with age.But the rural area and Huangpu area have the same major allergens： dermato-phagoides pteronyssinus and dermatophagoides farina.

关 键 词：过敏性疾病 变应原 皮肤点刺试验 

分 类 号：R725[医药卫生—儿科]