液晶修饰的有机-无机杂化硅整体柱的制备及电色谱性能  

Liquid Crystal Modified Organic-inorganic Hybrid Silica Monolithic Column for Capillary Electrochromatography

作　　者：冯睿[1] 沈敏[1] 陈浩[1] 黄载福[2] 曾昭睿[2] 

机构地区：[1]华中农业大学理学院,武汉430070 [2]武汉大学化学与分子科学学院,武汉430072

出　　处：《高等学校化学学报》2011年第1期50-55,共6页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20575049)资助

摘　　要：合成了一种含有端烯基的液晶4′-（ω-十一烯基氧）-4-联苯酚,通过偶氮二异丁腈（AIBN）引发的自由基聚合反应将其用于修饰含有烯基的有机-无机杂化硅整体柱.将该整体柱应用于毛细管电色谱,成功分离了萘酚、多环芳烃、酞酸酯和甾体激素,与未修饰柱的分离效果进行比较发现,疏水作用、π-π作用和氢键作用是导致分离的主要原因.以甾体激素为分离对象考察了柱内和柱间重现性,结果表明,5次连续进样的柱内迁移时间的RSD〈3.27%,所制备的3根柱子柱间迁移时间的RSD范围为7.39%-9.05%.A terminal-vinyl liquid crystal 4′-（ω-undecenyloxyl）-4-xenol was synthesized and used to modify terminal-vinyl organic-inorganic hybrid silica monolithic column by free radical polymerization procedure using 2,2′-azobis（2-methylpropionitrile）（AIBN） as an initiator.Naphthol,PAHs,phthalate ester and steroids were successfully separated on the column and the separation effects were compared with unmodified column.Mechanism was inferred to hydrophobic interaction,π-π interaction and hydrogen bonding.Reproducibilities of migration time for steroids was reasonable with RSD less than 3.27% for five consecutive within-column runs and RSDs were 7.39%— 9.05% for column-to-column measurements of three columns,respectively.

关 键 词：液晶 杂化硅整体柱 毛细管电色谱 

分 类 号：O657[理学—分析化学]