海口市136例丙型肝炎抗体可疑阳性献血者追访检查结果浅析  

Following-up to 136 blood donors with HCV antibody suspiciously positive in Haikou City

作　　者：吴多池 蔡兴权[2] 符慧杰[3] 

机构地区：[1]海口市结核病防治所检验科,海南海口570208 [2]海南省人民医院输血科,海南海口570311 [3]海南省血液中心业务质量管理科,海南海口570311

出　　处：《海南医学》2011年第1期103-104,共2页Hainan Medical Journal

摘　　要：目的为了降低输血风险,提高血源质量,了解海口无偿献血者丙型肝炎抗体可疑阳性(两种试剂检测结果一阴一阳)的原因,探讨今后减少丙型肝炎抗体可疑阳性的方法和途径。方法追访检查丙型肝炎抗体可疑阳性献血者,并采集其献血后三个月的标本,先用原两种国产试剂复检,仍为可疑阳性者用两种进口试剂再复检。结果成功追访检查的136名丙型肝炎抗体可疑阳性献血者绝大部分(97.79%)为假阳性。结论目前的国产试剂的特异性不够强是造成献血者丙型肝炎抗体可疑阳性淘汰的主要原因,应选用更高质量的检测试剂和加强检验人员的培训及引进先进的检测技术以减少丙型肝炎抗体假阳性。Objective To reduce the risk of blood transfusion,improve the quality of blood source,learn the deep reason causing two different test result of the suspicious positivity of unpaid blood donor＇s HCV antibody（two reagents resulted in negative and positive respectively）,and try to discuss the useful methods and approaches for the reduction of suspicious positivity of HCV antibody in the future.Methods Blood specimens with suspiciously positive HCV antibody,were collected after three months,which firstly using two domestic reagents re-examined.Those remaining suspiciously positive would be re-re-examined with two imported reagents.Results However,the vast majority（97.79%） of the successfully interviewed 136 blood donor＇s suspicious positivity turned out to be false positive after the follow-up retest.Conclusion The main reason causing blood donor＇s suspicious positive HCV antibody is the weak effect of current domestically reagents.In order to reduce HCV antibody false positivity,higher-quality test reagents as well as strengthening of inspection personnel training should be adopted in addition to the bringing in of advanced detection technology.

关 键 词：可疑阳性 丙型肝炎抗体 ELISA/随访复检 献血者 

分 类 号：R512.63[医药卫生—内科学]