水产常用抗菌药物对锯缘青蟹酚氧化酶的影响  

Effect of Common Antibiotics in Aquaculture on Phenoloxidase Activity in Mud Crab

作　　者：王海潮[1,2] 赵海泉[1] 钱冬[3] 潘清清 

机构地区：[1]安徽农业大学生命科学学院,安徽合肥230036 [2]宿州学院化学与生命科学系,安徽宿州234000 [3]浙江淡水水产研究所,浙江湖州313001 [4]浙江三门县海洋与渔业局,浙江三门317100

出　　处：《水产科学》2011年第1期38-41,共4页Fisheries Science

基　　金：浙江省科技厅重大科技攻关项目(2005C12038);宿州学院自然科学基金资助项目(2009yzk07);安徽省教育厅自然科学研究项目(kj2009b278z)

摘　　要：研究了喹诺酮类等17种常见抗菌药物对青蟹酚氧化酶的影响。试验结果表明,药物质量浓度为500μg/ml时,所有抗菌药物对青蟹酚氧化酶（PO）均有明显抑制作用;药物质量浓度为5~10μg/ml时（常规使用剂量）,庆大霉素、卡那霉素和丁胺卡那霉素等5种药物的PO抑制率为10%~25%;诺氟沙星、环丙沙星和氧氟沙星等6种药物的PO抑制率为5%~10%,抑制作用较弱;恩诺沙星和红霉素等4种药物的PO抑制率均小于5%,对青蟹PO无明显影响;低剂量阿维菌素和氟苯尼考对青蟹有免疫促进作用。Effects of 17 common antibiotics used in aquaculture such as quinolones,aminoglycosides,tetracyclines,and macrolides on phenoloxidase（PO）as an important immunnological index were studied in mud crab Scylla serrate.The results showed that all the antibiotics had apparent inhibition on PO at a concentration of 500 μg/ml.The gentamicin,kanamycin,and amikliin were found to have inhibition rate（HI）of 10%～25% at the dose of 5～10 μg/ml.Norfloxacin,ciprofloxacin,ofloxacin and other three antibiotics showed weak inhibition,with HI of 5%～10% at common dose.The erythromycin,enrofloxacin and other two antibiotics had HI of below 5%;avilamycin and florfenicol showed enhancing effects on PO in the crab.

关 键 词：抗菌药物 锯缘青蟹 酚氧化酶 影响 

分 类 号：S968.251[农业科学—水产养殖]