用超声背向散射参数评价心肌纤维化的临床研究  

作　　者：钱蕴秋[1] 周晓东[1] 张军[1] 李军[1] 陈宇翔[1] 

机构地区：[1]第四军医大学西京医院超声诊断科,西安710032

出　　处：《心功能杂志》1999年第3期157-158,168,共3页

摘　　要：为评价超声背向散射参数判定心肌组织纤维化的临床价值。采用 Ｈ Ｐ Ｓ Ｏ Ｎ Ｏ Ｓ２５００ 型超声检查仪观测２４ 例陈旧性心肌梗死（ Ｏ Ｍ Ｉ）患者梗死灶、３８ 例扩张型心肌病（ Ｄ Ｃ Ｍ ）和 ４５ 例Ⅱ型糖尿病（ Ｄ Ｍ）患者、正常对照组 ４０ 例室间隔、左室后壁心肌的背向散射参数——背向散射积分（ Ｉ Ｂ Ｓ）和 Ｉ Ｂ Ｓ的心动周期变化幅度（ Ｃ Ｖ Ｉ Ｂ）。结果： Ｏ Ｍ Ｉ梗死灶、 Ｄ Ｃ Ｍ 和Ⅱ型 Ｄ Ｍ 患者心肌的校正 Ｉ Ｂ Ｓ（ Ｉ Ｂ％ ）平均值均显著增大， Ｃ Ｖ Ｉ Ｂ均降低或出现 Ｉ Ｂ Ｓ曲线形态明显异常。 Ｉ Ｂ％ 、 Ｃ Ｖ Ｉ Ｂ对 Ｏ Ｍ Ｉ、 Ｄ Ｃ Ｍ、 Ｄ Ｍ 均有较高的阳性预告值和阴性预告值。结论：背向散射参数对判定心肌病变、判断心肌纤维化程度较为客观、简便，有较高的临床应用价值。A clinical study in assessm ent of m yocardial fibrosis w ith ultrasonicbackscatter param eters Zhu Yongsheng, Qian Yunqiu, Zhou Xiaodong, Zhang Jun, Li Jun, Chen Yuxiang Departm ent of Ultrasound, Xijing Hospital, Fourth M illitary University, Xi′an 710032 Abstract 　 W e sought to assess the value of ultrasonic backscatter param eters in thedeterm ination of m yocardial fibrosis. M yocardial ultrasonic backscatter param eters of patientsw ith old m yocardial infarction ( O M I, 24 cases), dilated cardiom yopathy ( D C M , 38 cases),diabetes m ellitus ( D M ,45 cases) and 40 m em bers of norm al control group w ere m easured by acom m ercially available m odified realtim e backscatter signal 2 D im aging system ( H P S O N O S2500). Results: Tim eaveraged values of corrected m yocardial I B S ( I B% ) of previously infarctedm yocardium foci and I V S or L V P W of patients w ith D C M or D M w ere all significantly greaterthan those of the norm al. For m ost patients, patterns of tim e I B S curve turned out to beabnorm al and C V I B values decreased greatly. I B% , C V I B brought about high positive ornegative predictive values to O M I, D C M and D M . Conclusion: Ultrasonic backscatter w as usefulin determ ining m yocardial abnorm ality and assessing the degree of m yocardial fibrosis. It is anobjective and direct technique for clinicalapplication. Key w ords　 ultrasonic backscatter 　 m yocardial fibrosis　 tissue characterization

关 键 词：超声背向散射 心肌纤维化 组织定征 

分 类 号：R542.204[医药卫生—心血管疾病] R445.1[医药卫生—内科学]