应用肌电图定量分析前庭功能障碍的实验研究  

Experimental study on the EMG quantitative analyses of vestibular dysfunction

作　　者：迟放鲁[1] 王正敏[1] 吴琍雯[1] 

机构地区：[1]上海医科大学眼耳鼻喉科医院卫生部听觉医学重点实验室,上海市200031

出　　处：《中华航海医学杂志》1999年第3期155-158,共4页

基　　金：上海市卫生系统跨世纪学科带头人培养百人计划项目

摘　　要：目的　通过肌电图与姿势反射的相关性研究，探讨肌电图检测前庭功能障碍的意义。方法　将受试大鼠分成四组，Ａ组：正常大鼠９只；Ｂ组：前庭功能障碍１周内大鼠１２只；Ｃ组：前庭功能障碍３ 个月大鼠３只；Ｄ组：前庭损伤５ 个月后功能恢复大鼠６ 只。记录单侧前庭功能障碍时大鼠颈项部头夹肌静息状态的肌电活动和眼震电图。结果　正常大鼠两侧头夹肌肌电图振幅相等，为１５ μＶ；单侧前庭功能障碍急性期同侧肌电振幅降低，为２～３ μＶ，对侧增加到２５～３５ μＶ；恢复期同侧肌电振幅逐渐增加，前庭功能完全恢复后两侧肌电振幅恢复相等。结论　重力拮抗肌肌电图可敏感反映前庭功能异常时前庭脊髓反射的姿势反射状况，为航海者提供一个检测前庭功能的指标。Objective To clarify the significance of EMG examination of vestibular dysfunction by means of a correlated study of EMG change and posture response. Methods The experimental rats were divided into four groups. Group A: 9 normal rats; Group B: 12 rats within 1 week of vestibular dysfunction; Group C: 3 rats with vestibular dysfunction of 3 months; Group D: 6 rats with recovered vestibular function after 5 months of injury. EMG of neck muscle(M splenius) on both sides as well as nystagmogram during the unilateral vestibular dysfunction period were recorded. Results The amplitudes of EMG were equal on both sides(15μV) in group A. During acute unilateral vestibular dysfunction period, the ipsolateral EMG amplitude decreased to 2~3 μV but increased to 25~35μV contralaterally. During period of recovery, the ipsolateral EMG amplitude increased gradually. After 5 months, with complete recovery of vestibular function the EMG amplitudes returned to same on both sides. Conclusions As a valuable index, EMG could be used to examine vestibulospinal reflexes and posture response in vestibular dysfunction state, and it is useful for the examination of vestibular function in seamen.

关 键 词：前庭功能障碍 肌电图 姿势反射 前庭脊髓反射 

分 类 号：R835.104[医药卫生—航空、航天与航海医学]