中风芪红利水饮治疗缺血性中风的临床疗效及对血管内皮功能的影响  

Zhongfeng Qihong Lishui Liquid(ZFQHLSL)'s Clinical Effection in Treating Ischemic Cerebral Stroke(CIS) and the Effection on Vasoactive Function

作　　者：曹玮[1] 张振强[2] 王新志[3] 

机构地区：[1]河南中医学院第三附属医院,河南郑州450008 [2]河南中医学院,河南郑州450008 [3]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2011年第1期74-76,共3页Acta Chinese Medicine

基　　金：河南省教育厅自然科学研究(编号:2009A360026)

摘　　要：目的:观察中风芪红利水饮治疗缺血性中风的临床疗效及对血管内皮功能的影响,进一步探讨中风芪红利水饮治疗缺血性中风的作用机制。方法:将120例患者随机分为对照组与治疗组各60例,两组均在西药治疗基础上,对照组采用步长脑心通胶囊治疗,治疗组采用中风芪红利水饮治疗。观察治疗前后临床疗效、神经功能缺损积分及生活能力积分变化、血浆内皮素(endothelin,ET)及NO的变化情况。结果:临床有效率治疗组为91.67%,对照组为75.00%,2组比较,差异有显著性意义(P<0.05),神经功能缺损积分及生活能力积分变化、血浆ET及NO的变化情况差异均有统计学意义,提示治疗组疗效优于对照组。结论:中风芪红利水饮结合西药治疗缺血性中风疗效确切,安全性好,有较高的临床应用价值。Objective： To observe Zhongfeng Qihong Lishui Liquid（ZFQHLSL）＇s clinical effection on Ischemic Cerebral Stroke（CIS） and the effect on blood vessel endothelium function,furtherly discuss Zhongfeng Qihong Lishui Liquid＇s mechanism of action to Ischemic Cerebral Stroke.Methods：120 patients were randomly divided into control group（60 cases） and treatment group（60 cases）,Both groups on the basis of western medicine,the control group were treated by buchangnaoxintong capsule and the control group were treated by ZFQHLSL. The changment of the clinical effection 、the changment of the scores of the nerve function＇s deficiency and living capability and the changment of the plasma ET and nitric oxide（NO）were observed before and after treatment.Results：In the total clinical effective rate,the treatment group was 91.67%,the control group was 75.00%.There was significantly differences between two groups（P0.05）.There were statistical differences between the treatment group and the control group in the changment of the scores of the nerve function＇s deficiency and living capability and the changment of the ET and NO.The resuts shows that the trial group was apparently compared with control group in clinical effection.Conclusion：Zhongfeng Qihong Lishui Liquid is safe and effective in the treatment of Ischemic Cerebral Stroke.So it has a good clinical value.

关 键 词：缺血性中风 脑梗塞 血管内皮功能 中风芪红利水饮 

分 类 号：R255.2[医药卫生—中医内科学]