人胚胎时期生长激素对胚胎发育的影响  

Effect of growth hormone in human fetals in the growth fetal

作　　者：卫朝霞[1] 李杭生[1] 张华[2] 马占敏[3] 聂正明[2] 

机构地区：[1]河南职工医学院,郑州450003 [2]河南医科大学人体解剖教研室 [3]郑州市妇幼保健院

出　　处：《河南医学研究》1999年第3期196-198,共3页Henan Medical Research

摘　　要：目的： 探讨不同胎龄人胎垂体生长激素含量对胚胎生长发育的影响。方法： 用双抗体放射免疫分析方法研究３８ 例正常人胎和８ 例无脑儿的血清及垂体生长激素含量。结果： ①在胎２１ 周以前，垂体所含生长激素量逐渐增加，２１ ～２４ 周达高峰，此后呈下降趋势，但仍高于２１ 周以前的水平。②正常人胎血清生长激素含量，有随胎龄增加而上升趋势。③正常胎儿垂体生长激素含量与其身长、体重呈正相关，无脑儿身长、体重与生长激素含量无关。结论： 生长激素虽然在胚胎生长发育中起重要作用，但不是唯一的。Objective: We investigated the growth hormone in human fetal pituitary and the growth of fetal.Methods:By the radioimmunoassay with double antibodies 38 normal fetals and 8 human anencephalic fetuses were studied.Results: ①The GH content of fetal pituitary increased gradually with fetal ages, and reached a maximul level at the 21th week and then fell gradually, but it was still higher than that in the 24th week.②Serum concentration of GH was variable, but increased with fetal ages.③The body weight and length of normal fetal were correlated positively with pituitary growth hormone content. The body weight and length of anencephalic fetuses showed no correlation with pituitary grouth hormone content.Conclusion:Although the growth hormone may play important role in the growth of human fetus,but it is not only one. These results provided new data for study of the control of the growth in human fetal.

关 键 词：生长激素 胚胎 生长发育 

分 类 号：R714.51[医药卫生—妇产科学] Q575.11[医药卫生—临床医学]