普贝生用于足月引产的临床效果评价  

Clinical Evaluation of Propess for Induced Labor of Term Pregnancy

作　　者：冯浩[1] 郭伟[1] 王莉[1] 

机构地区：[1]山东省千佛山医院妇产科,山东济南250014

出　　处：《食品与药品》2011年第1期44-46,共3页Food and Drug

摘　　要：目的探讨普贝生用于足月妊娠引产的临床效果。方法随机将156例足月妊娠孕妇分为两组,分别用普贝生和缩宫素引产,比较两组的宫颈评分、临产和分娩情况及不良反应。结果普贝生组引产成功率高(96.25%vs78.95%),临产时间缩短(10.87±5.67vs25.89±10.23),产程短(5.32±2.24vs11.92±3.12),对新生儿无不良影响。结论普贝生用于足月引产安全、有效,对母儿无明显的不良影响。Objective To explore the effectiveness of continuously released prostaglandin E2 suppository （propess） used for induced labor of term pregnancy. Methods A prospective case control clinical study was carried out involved 156 cases of term pregnancies. Propess was used in 80 cases and oxytocin was used in 76 cases. The rate of cervical ripening, time from induction to delivery, duration of stage, and side effects of drugs were compared between the two groups. Results Compared with oxytocin, the rate of cervical ripening was higher in propess group （96.25% vs. 78.95% ）, with lower induction-delivery interval （10.87 ±5.67 vs. 25.89± 10.23）, shorter stage of labor （5.32 ±2.24 vs. 11.92 ± 3.12）. No side effect was observed in the fetal and neonatal conditions of the two groups. Conclusion Propess can be used in induced labor safely and effectively, furthermore no maternal and fetus damages are produced.

关 键 词：前列腺素E2 缩宫素 引产 

分 类 号：R719.3[医药卫生—妇产科学]