消栓颗粒治疗病毒性心肌炎的疗效及其对IL-2、PFP的影响  

The Therapeutic Effect of Xiaoshuan Grana Treat Viral Myocarditis and the Effect of IL-2 and PFP

作　　者：赵利[1] 

机构地区：[1]福建省人民医院八区心内科,福州350004

出　　处：《光明中医》2011年第1期54-55,共2页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的探讨消栓颗粒治疗病毒性心肌炎的作用机制。方法收集60例病毒性心肌炎病例,随机分为对照组和治疗组,疗程3～4周,治疗前后检测心肌酶学(CK、CK-MB),血清IL-2及淋巴细胞穿孔素表达水平(PFP)及疗效评价。结果应用消栓颗粒治疗病毒性心肌炎血清IL-2下降、外周血淋巴细胞穿孔素表达水平下降有统计学意义(P<0.05)。结论消栓颗粒治疗病毒性心肌炎有效,免疫作用机理可能与降低外周血IL-2、淋巴细胞穿孔素表达有关。Objective：Initial research the mechanisms of Xiaoshuan grana treat viral myocarditis.Methods：60 viral myocarditis cases were collected,random divided into control groups and treat group.Course of treatment were 3 ～ 4 weeks,every patient examine CK,CK-MB,IL-2,PFP and evaluate therapeutic effect after and before treatment.Results：Xiaoshuan grana treat viral myocarditis had statistical significance with IL-2 and PFP subside（P〈0.05）.Conclusion：Xiaoshuan grana treat viral myocarditis was utility.Immunifaction mechanism may relate with the subside of IL-2 concentration and PFP express level.

关 键 词：消栓颗粒 病毒性心肌炎 白细胞介素-2 淋巴细胞穿孔素 

分 类 号：R259[医药卫生—中西医结合]