瘤果槲寄生化学成分的研究(Ⅱ)  

Constituents of Viscum ovalifolium DC(Ⅱ)

作　　者：杨燕军[1] 沙聪威[2] 陈梅果[1] 

机构地区：[1]广东省中药研究所,广东食品药品职业学院,广州510520 [2]广东省药物研究所,广州510440

出　　处：《中国药学杂志》2011年第1期11-13,共3页Chinese Pharmaceutical Journal

基　　金：广东省科技计划项目(2008B030301195);广东省中医药局重点及一般项目(2008435、2008200)

摘　　要：目的进一步研究瘤果槲寄生的化学成分。方法应用硅胶柱色谱、凝胶柱色谱等各种色谱技术对瘤果槲寄生化学成分进行分离、纯化,并利用理化数据分析和光谱分析方法鉴定化合物的结构。结果分离并鉴定出8个三萜及三萜皂苷化合物,分别为羽扇豆醇硬脂酸酯(Ⅰ)、羽扇豆醇棕榈酸酯(Ⅱ)、β-香树脂醇乙酸酯(Ⅲ)、常春藤皂苷元(Ⅳ)、丝石竹酸(Ⅴ)、常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖苷(Ⅵ)、常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖基(2→1)-β-D-吡喃葡萄糖苷(Ⅶ)、3-O-α-L-吡喃阿拉伯糖-常春藤皂苷元-28-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖苷(Ⅷ)。结论化合物Ⅰ～Ⅷ为首次从本植物中分离得到,其中化合物Ⅳ～Ⅷ为首次从槲寄生属植物中分离得到。OBJECTIVE To study the chemical constituents of Viscum ovalifolium DC,further.METHODS Chemical constituents were isolated from the title plant by various chromatographic methods such as silica gel medium pressure column,sephadex LH-20 column chromatography,et al.Their structures were elucidated by physiochemical and spectral analysis.RESULTS Eight triterpenoids and triterpenoid saponins were isolated and identified as lupeol stearate（Ⅰ）,lupeol palmitate（Ⅱ）,β-amyrin acetate（Ⅲ）,hederagenin（Ⅳ）,gypsogenic acid（Ⅴ）,hederagenin-3-O-α-L-arabinopyranoside（Ⅵ）,hederagenin-3-O-α-L-arabinopyranoyl-（2→1）-O-β-D-glucopyranoside（Ⅶ）,3-O-α-L-arabinopyranoyl-hederagenin-28-O-β-D-glucopyranosyl-（1→6）-β-D-glucopyranoside（Ⅷ）.CONCLUSION Compound Ⅰ-Ⅷ were isolated from this plant for the first time,compound Ⅳ-Ⅷ were isolated from Viscum for the first time.

关 键 词：瘤果槲寄生 化学成分 结构鉴定 

分 类 号：R284[医药卫生—中药学]